Frova and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Abilify (aripiprazole). Common drug interactions include dizziness among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Frova and Abilify. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.



On Jul, 21, 2026

27 people who take Frova and Abilify together, and have interactions are studied.

Frova and Abilify drug interactions.

What are the common drug interactions of Frova and Abilify, by gender? *:

female:

  1. Dizziness
  2. Fibula fracture
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  6. Renal failure (kidney dysfunction)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Sinusitis (inflammation of sinus)
  9. Somnambulism (sleep walking)
  10. Tibia fracture (fracture of lower leg bone)

male:

  1. Blood glucose increased
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Tardive dyskinesia (a disorder that involves involuntary movements)
  5. Type 1 diabetes mellitus
  6. Type 2 diabetes mellitus

What are the common drug interactions of Frova and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Emotional disorder
  2. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  3. Sleep-related eating disorder (abnormal eating patterns during the night)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  3. Vomiting
  4. Abnormal behaviour
  5. Chronic kidney disease
  6. Dyspepsia (indigestion)
  7. Memory impairment
  8. Mood altered (changes in mood)
  9. Muscle spasms (muscle contraction)
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

50-59:

  1. Activities of daily living impaired
  2. Alanine aminotransferase increased
  3. Anxiety
  4. Arthralgia (joint pain)
  5. Aspartate aminotransferase increased
  6. Asthenia (weakness)
  7. Asthma
  8. Blood alkaline phosphatase increased
  9. Blood cholesterol increased
  10. Blood creatine decreased

60+:

  1. Chronic kidney disease
  2. Headache (pain in head)
  3. Renal failure (kidney dysfunction)
  4. Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 33.33%
  2. Immunodeficiency Common Variable: 5 people, 18.52%
  3. Pain: 3 people, 11.11%
  4. High Blood Pressure: 3 people, 11.11%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
  6. Nausea (feeling of having an urge to vomit): 2 people, 7.41%
  7. High Blood Cholesterol: 2 people, 7.41%
  8. Drug Hypersensitivity: 2 people, 7.41%
  9. Diabetes: 2 people, 7.41%
  10. Cyclic Vomiting Syndrome (prolonged episodes of severe nausea, vomiting): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Frova and Abilify?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Frova and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Frova:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Frova and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on frovatriptan succinate and aripiprazole (the active ingredients of Frova and Abilify, respectively), and Frova and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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