Frova and Vitamin d3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Vitamin d3 (cholecalciferol). Common drug interactions include blindness unilateral among females and dry eye among males.

The phase IV clinical study analyzes what interactions people have when they take Frova and Vitamin d3. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,172 Vitamin d3 users. Check the latest studies of Vitamin d3.



On Aug, 04, 2026

14 people who take Frova and Vitamin d3 together, and have interactions are studied.

Frova and Vitamin d3 drug interactions.

What are the common drug interactions of Frova and Vitamin D3, by gender? *:

female:

  1. Blindness unilateral
  2. Ear infection
  3. Eye infection
  4. Nausea (feeling of having an urge to vomit)
  5. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  6. Photosensitivity reaction
  7. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Blood pressure systolic increased
  10. Bone pain

male:

  1. Dry eye (lack of adequate tears)
  2. Neck pain
  3. Vision blurred

What are the common drug interactions of Frova and Vitamin D3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal discomfort
  2. Asthenia (weakness)
  3. Blindness unilateral
  4. Ear infection
  5. Eye infection
  6. Eye irritation
  7. Eye pain
  8. Headache (pain in head)
  9. Nausea (feeling of having an urge to vomit)
  10. Pharyngitis (inflammation of the pharynx, causing a sore throat)

20-29:

n/a

30-39:

  1. Obesity (having too much body fat)
  2. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  3. Therapeutic response unexpected
  4. Weight decreased

40-49:

  1. Abnormal behaviour
  2. Memory impairment
  3. Mood altered (changes in mood)
  4. Muscle spasms (muscle contraction)
  5. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  6. Pain

50-59:

  1. Asthenia (weakness)
  2. Eye irritation
  3. Eye pain
  4. Gait disturbance
  5. Headache (pain in head)
  6. Infusion related reaction
  7. Myalgia (muscle pain)
  8. Tendonitis (a condition that causes pain and swelling of tendons)
  9. Visual field defect
  10. Abdominal pain

60+:

  1. Dizziness
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Suicidal ideation
  5. Neck pain
  6. Overdose
  7. Vision blurred
  8. Blood pressure systolic increased
  9. Bone pain
  10. Dry eye (lack of adequate tears)

What are the existing conditions these people have? *

  1. Optic Neuritis (optic nerve inflammation): 3 people, 21.43%
  2. Osteoporosis (bones weak and more likely to break): 3 people, 21.43%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 21.43%
  4. High Blood Cholesterol: 3 people, 21.43%
  5. Stress And Anxiety: 3 people, 21.43%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 14.29%
  8. Hypersensitivity: 2 people, 14.29%
  9. Insomnia (sleeplessness): 2 people, 14.29%
  10. Multiple Allergies (allergy to multiple agents): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Frova and Vitamin d3?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Frova and Vitamin d3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Frova:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin d3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Frova and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin d3 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on frovatriptan succinate and cholecalciferol (the active ingredients of Frova and Vitamin d3, respectively), and Frova and Vitamin d3 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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