Furosemide and Zinacef drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Furosemide (furosemide) and Zinacef (cefuroxime sodium). Common drug interactions include skin discolouration among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Furosemide and Zinacef. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.
What is Furosemide?
Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.
What is Zinacef?
Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.
87 people who take Furosemide and Zinacef together, and have interactions are studied.

What are the common drug interactions of Furosemide and Zinacef, by gender? *:
female:
- Skin discolouration (change of skin colour)
- Renal cyst (kidney cyst)
- Anaemia (lack of blood)
- Bone disorder
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Cellulitis (infection under the skin)
- Culture urine positive
- Disability
- Dysphagia (a condition in which swallowing is difficult or painful)
- Ear pain
male:
- Renal failure (kidney dysfunction)
- Injury
- Multi-organ failure (multisystem organ failure)
- Stress
- Dyspnoea (difficult or laboured respiration)
- Cardiac failure congestive
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pyrexia (fever)
- Acute respiratory failure
- Blood urea increased
What are the common drug interactions of Furosemide and Zinacef, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Brain injury
- Death
- Emotional distress
- Fear
- Injury
- Multi-organ failure (multisystem organ failure)
- Pain
- Renal failure (kidney dysfunction)
10-19:
n/a
20-29:
- Anaphylactic reaction (serious allergic reaction)
- Angioedema (rapid swelling of the dermis)
- Anxiety
- Skin discolouration (change of skin colour)
30-39:
- Back pain
- Chronic kidney disease
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Dysuria (painful or difficult urination)
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
- Haematuria (presence of blood in urine)
- Haemoglobin decreased
- Hydronephrosis (water inside the kidney)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
40-49:
- Renal failure (kidney dysfunction)
- Anxiety
- Chronic kidney disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Fear
- Injury
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pain
- Renal failure chronic (long lasting kidney dysfunction)
50-59:
- Cardiac failure
- Cardiomyopathy (weakening of the heart muscle)
- Cellulitis (infection under the skin)
- Collapse of lung (functional breakdown of lung)
- Depressed level of consciousness
- Depression
- Dyspnoea (difficult or laboured respiration)
- Mitral valve incompetence (inefficient heart valve)
- Myopathy (a muscular disease in which the muscle fibres do not function)
- Nausea (feeling of having an urge to vomit)
60+:
- Injury
- Pain
- Back pain
- Bone disorder
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Cellulitis (infection under the skin)
- Culture urine positive
- Disability
- Dysphagia (a condition in which swallowing is difficult or painful)
- Ear pain
What are the existing conditions these people have? *
- High Blood Cholesterol: 8 people, 9.20%
- High Blood Pressure: 7 people, 8.05%
* Approximation only. Some reports may have incomplete information.
Do you take Furosemide and Zinacef?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Furosemide (316,095 reports)
- Zinacef (1,802 reports)
Browse all drug interactions of Furosemide and Zinacef:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zinacef:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Furosemide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zinacef and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on furosemide and cefuroxime sodium (the active ingredients of Furosemide and Zinacef, respectively), and Furosemide and Zinacef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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