Fycompa and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fycompa (perampanel) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include seizure among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Fycompa and Hydrochlorothiazide. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Fycompa?

Fycompa has active ingredients of perampanel. eHealthMe is studying from 4,387 Fycompa users. Check the latest studies of Fycompa.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

On Jul, 27, 2026

14 people who take Fycompa and Hydrochlorothiazide together, and have interactions are studied.

Fycompa and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Fycompa and Hydrochlorothiazide, by gender? *:

female:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal pain
Asthenia (weakness)
Back pain
Blood iron decreased
Cough
Decreased appetite
Diarrhoea
Dizziness postural
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)

male:

Agitation (state of anxiety or nervous excitement)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fall
Fatigue (feeling of tiredness)
Haematoma (collection of blood outside the blood vessels)
Intervertebral disc degeneration (spinal disc degeneration)
Joint injury
Palpitations (feelings or sensations that your heart is pounding or racing)
Road traffic accident
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Fycompa and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

Drug withdrawal convulsions

2-9:

n/a

10-19:

n/a

20-29:

Acute respiratory failure
Encephalopathy (functioning of the brain is affected by some agent or condition)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

30-39:

n/a

40-49:

Polycythaemia (proportion of blood volume that is occupied by red blood cells increases)

50-59:

Blood iron decreased
Cough
Decreased appetite
Diarrhoea
Dizziness postural
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Flushing (the warm, red condition of human skin)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematochezia (passage of stools containing blood)

60+:

Balance disorder
Calcinosis (calcium deposits in any soft tissue)
Drug hypersensitivity
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the existing conditions these people have? *

Back Pain: 3 people, 21.43%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 21.43%
Pain In Extremity: 3 people, 21.43%
Pain: 3 people, 21.43%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 21.43%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 3 people, 21.43%
Joint Pain: 3 people, 21.43%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 14.29%
Insomnia (sleeplessness): 1 person, 7.14%
Dry Eyes (lack of adequate tears): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Fycompa and Hydrochlorothiazide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously