Gaba and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gaba (gaba (gamma - aminobutyric acid)) and Gabapentin (gabapentin). Common drug interactions include constipation among females and acne among males.

The phase IV clinical study analyzes what interactions people have when they take Gaba and Gabapentin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Gaba?

Gaba has active ingredients of gaba (gamma - aminobutyric acid). It is often used in stress and anxiety. eHealthMe is studying from 428 Gaba users. Check the latest studies of Gaba.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in peripheral neuropathy. eHealthMe is studying from 322,990 Gabapentin users. Check the latest studies of Gabapentin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

26 people who take Gaba and Gabapentin together, and have interactions are studied.

What are the common drug interactions of Gaba and Gabapentin, by gender? *:

female:

Constipation
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema peripheral (superficial swelling)
Pelvic discomfort
Renal impairment (severely reduced kidney function)

male:

Acne (skin problems that cause pimples)
Gait disturbance
Immobile (not moving)

What are the common drug interactions of Gaba and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Skin wrinkling (wrinkle on skin)
Tendon rupture (tear of tendon)
Tinnitus (a ringing in the ears)
Visual impairment
Disease recurrence
Abnormal behaviour
Abnormal dreams
Acne (skin problems that cause pimples)
Adrenal disorder
Arthralgia (joint pain)

40-49:

Headache (pain in head)
Aphasia (damage to the parts of the brain that control language)
Asthma
Aura
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Confusional state
Cough
Depressed mood

50-59:

Application site erythema (redness of the skin at application site)
Application site irritation
Application site pain
Application site rash
Nightmare (unpleasant dream)
Suicidal ideation

60+:

Abdominal pain upper
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema peripheral (superficial swelling)
Pelvic discomfort
Renal impairment (severely reduced kidney function)
Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
Vomiting

What are the existing conditions these people have? *

Pain: 4 people, 15.38%
Neuralgia (pain in one or more nerves): 4 people, 15.38%
Urination - Painful: 3 people, 11.54%
Sleep Disorder: 3 people, 11.54%
Nausea And Vomiting: 3 people, 11.54%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.54%
Muscle Spasms (muscle contraction): 3 people, 11.54%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 3 people, 11.54%
Endometrial Cancer: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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