Gabapentin and Feldene drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gabapentin (gabapentin) and Feldene (piroxicam). Common drug interactions include activities of daily living impaired among females and rash among males.
The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Feldene. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.
What is Gabapentin?
Gabapentin has active ingredients of gabapentin. It is often used in peripheral neuropathy. eHealthMe is studying from 322,990 Gabapentin users. Check the latest studies of Gabapentin.
What is Feldene?
Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
80 people who take Gabapentin and Feldene together, and have interactions are studied.

What are the common drug interactions of Gabapentin and Feldene, by gender? *:
female:
- Activities of daily living impaired
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
- Asthma
- Cardiomegaly (increased size of heart than normal)
- Confusion
- Contusion (a type of hematoma of tissue in which capillaries)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Diarrhoea
- Dysarthria (speech disorder)
male:
- Rash
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
- Arteriosclerosis (thickening and hardening of arteries)
- Back pain
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
- Blood glucose increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure
What are the common drug interactions of Gabapentin and Feldene, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Eye pain
- Hypoaesthesia (reduced sense of touch or sensation)
- Weight increased
30-39:
- Abortion spontaneous (naturally occurring miscarriage)
- Blood magnesium decreased
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
40-49:
- Fatigue (feeling of tiredness)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Asthenia (weakness)
- Asthma
- Blood glucose increased
- Dizziness
- Drug ineffective
- Dyspepsia (indigestion)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
50-59:
- Drug effect decreased
- Drug ineffective
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Headache (pain in head)
- Hysterectomy
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Surgery
- Vitamin k increased
- Weight decreased
- Bradycardia (abnormally slow heart action)
60+:
- Fall
- Chronic kidney disease
- Cardiac disorder
- Cellulitis (infection under the skin)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dizziness
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Erythema (redness of the skin)
What are the existing conditions these people have? *
- Pain: 18 people, 22.50%
- High Blood Cholesterol: 17 people, 21.25%
- High Blood Pressure: 9 people, 11.25%
- Back Pain: 9 people, 11.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.00%
- Neuralgia (pain in one or more nerves): 7 people, 8.75%
- Depression: 5 people, 6.25%
- Stress And Anxiety: 4 people, 5.00%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 5.00%
- Migraine (headache): 4 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Gabapentin and Feldene?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gabapentin (322,990 reports)
- Feldene (3,913 reports)
Browse all drug interactions of Gabapentin and Feldene:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gabapentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Feldene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gabapentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Feldene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin and piroxicam (the active ingredients of Gabapentin and Feldene, respectively), and Gabapentin and Feldene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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