Gabapentin and Tylenol w/ codeine no. 3 drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gabapentin (gabapentin) and Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate). Common drug interactions include arthritis among females and vomiting among males.
The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.
What is Gabapentin?
Gabapentin has active ingredients of gabapentin. It is often used in peripheral neuropathy. eHealthMe is studying from 322,990 Gabapentin users. Check the latest studies of Gabapentin.
What is Tylenol w/ codeine no. 3?
Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
100 people who take Gabapentin and Tylenol w/ codeine no. 3 together, and have interactions are studied.

What are the common drug interactions of Gabapentin and Tylenol W/ Codeine No. 3, by gender? *:
female:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Hypertension (high blood pressure)
- Abdominal pain
- Anaemia (lack of blood)
- Bone pain
- Insomnia (sleeplessness)
- Constipation
- Depression
- Diarrhoea
- Headache (pain in head)
male:
- Vomiting
- Diarrhoea
- Hypoaesthesia (reduced sense of touch or sensation)
- Oedema peripheral (superficial swelling)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Wound infection
- Abdominal abscess (collection of pus in abdomen)
- Asthenia (weakness)
- Confusional state
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Gabapentin and Tylenol W/ Codeine No. 3, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dyspnoea (difficult or laboured respiration)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Injury
- Mobility decreased (ability to move is reduced)
- Pain in extremity
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
- Dizziness
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Muscular weakness (muscle weakness)
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaemia (lack of blood)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthma
40-49:
- Anaemia (lack of blood)
- Diarrhoea
- Vomiting
- Wound infection
- Abdominal abscess (collection of pus in abdomen)
- Ascites (accumulation of fluid in the abdominal cavity)
- Hepatitis c
- Malaise (a feeling of general discomfort or uneasiness)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Arthralgia (joint pain)
50-59:
- Emotional distress
- Headache (pain in head)
- Abdominal pain
- Acute sinusitis
- Affective disorder (mental disorder)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bladder cyst
- Bone disorder
60+:
- Anxiety
- Depression
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Confusional state
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Fall
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hemiplegia (paralysis of one side of the body)
- Hyperhidrosis (abnormally increased sweating)
What are the existing conditions these people have? *
- Depression: 12 people, 12.00%
- Stress And Anxiety: 11 people, 11.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 9.00%
- Neoplasm Malignant (cancer tumour): 8 people, 8.00%
- High Blood Cholesterol: 8 people, 8.00%
- High Blood Pressure: 7 people, 7.00%
- Type 2 Diabetes: 6 people, 6.00%
- Osteoporosis (bones weak and more likely to break): 6 people, 6.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 5.00%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Gabapentin and Tylenol w/ codeine no. 3?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gabapentin (322,990 reports)
- Tylenol w/ codeine no. 3 (4,920 reports)
Browse all drug interactions of Gabapentin and Tylenol w/ codeine no. 3:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gabapentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tylenol w/ codeine no. 3:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gabapentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tylenol w/ codeine no. 3 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin and acetaminophen; codeine phosphate (the active ingredients of Gabapentin and Tylenol w/ codeine no. 3, respectively), and Gabapentin and Tylenol w/ codeine no. 3 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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