Gabitril and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gabitril (tiagabine hydrochloride) and Actonel (risedronate sodium). Common drug interactions include xanthopsia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Gabitril and Actonel. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Gabitril?

Gabitril has active ingredients of tiagabine hydrochloride. It is often used in epilepsy. eHealthMe is studying from 2,230 Gabitril users. Check the latest studies of Gabitril.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.



On Jul, 12, 2026

13 people who take Gabitril and Actonel together, and have interactions are studied.

Gabitril and Actonel drug interactions.

What are the common drug interactions of Gabitril and Actonel, by gender? *:

female:

  1. Xanthopsia (yellow vision)
  2. Femur fracture
  3. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  4. Pain
  5. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  6. Arthralgia (joint pain)
  7. Bone disorder
  8. Fracture displacement
  9. Fracture nonunion (permanent failure of healing following a broken bone)
  10. Groin pain

male:

  1. Arthralgia (joint pain)
  2. Bone disorder
  3. Mass
  4. Mobility decreased (ability to move is reduced)
  5. Monoparesis (one limb is very weak, but not completely paralyzed)
  6. Muscle injury
  7. Osteoporotic fracture (fracture due to weak bone)
  8. Pain
  9. Pathological fracture (broken bone caused by disease)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Gabitril and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Muscle injury
  2. Osteoporotic fracture (fracture due to weak bone)
  3. Pain
  4. Pathological fracture (broken bone caused by disease)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  7. Arthralgia (joint pain)
  8. Bone disorder
  9. Dysstasia (difficulty in standing)
  10. Femur fracture

40-49:

  1. Anxiety
  2. Asthenia (weakness)
  3. Dizziness
  4. Dyskinesia (abnormality or impairment of voluntary movement)
  5. Dysphemia (stammering or stuttering)
  6. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Pain in extremity
  9. Speech disorder
  10. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

  1. Groin pain
  2. Mobility decreased (ability to move is reduced)
  3. Osteoporotic fracture (fracture due to weak bone)
  4. Pathological fracture (broken bone caused by disease)
  5. Fall
  6. Mass
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Hip deformity
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Muscle haemorrhage (bleeding in muscle)

60+:

  1. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  2. Chest pain

What are the existing conditions these people have? *

  1. Stress And Anxiety: 1 person, 7.69%
  2. Pain: 1 person, 7.69%
  3. Muscle Spasms (muscle contraction): 1 person, 7.69%
  4. Blood Calcium Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Gabitril and Actonel?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gabitril and Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gabitril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gabitril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tiagabine hydrochloride and risedronate sodium (the active ingredients of Gabitril and Actonel, respectively), and Gabitril and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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