Gabitril and Cogentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gabitril (tiagabine hydrochloride) and Cogentin (benztropine mesylate). Common drug interactions include collapse of lung among females and convulsions among males.

The phase IV clinical study analyzes what interactions people have when they take Gabitril and Cogentin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Gabitril?

Gabitril has active ingredients of tiagabine hydrochloride. It is often used in epilepsy. eHealthMe is studying from 2,230 Gabitril users. Check the latest studies of Gabitril.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

On Jul, 13, 2026

14 people who take Gabitril and Cogentin together, and have interactions are studied.

Gabitril and Cogentin drug interactions.

What are the common drug interactions of Gabitril and Cogentin, by gender? *:

female:

Collapse of lung (functional breakdown of lung)
Developmental delay
Drug exposure during pregnancy
Dysmorphism (difference of body structure that is suggestive of a congenital disorder)
Cardiac disorder
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Blood pressure decreased
Body temperature decreased

male:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Incoherent (talking in a confused and unclear way)
Drug screen positive
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Splenomegaly (enlargement of spleen)
Agitation (state of anxiety or nervous excitement)
Ammonia increased
Ascites (accumulation of fluid in the abdominal cavity)
Delirium (wild excitement)

What are the common drug interactions of Gabitril and Cogentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac disorder
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Difficulty in walking
Granuloma (a small area of inflammation due to tissue injury)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hyperinsulinism (above normal level of insulin in the blood)
Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Body temperature decreased
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coma (state of unconsciousness lasting more than six hours)
Cyst (a closed sac)
Delirium (wild excitement)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 42.86%
Depression: 3 people, 21.43%
Stress And Anxiety: 1 person, 7.14%
Sleep Disorder: 1 person, 7.14%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
Psychotic Disorder: 1 person, 7.14%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 7.14%
Affective Disorder (mental disorder): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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