Gaviscon and Disipal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gaviscon (aluminum hydroxide; magnesium trisilicate) and Disipal (orphenadrine hydrochloride). Common drug interactions include sudden death among females.

The phase IV clinical study analyzes what interactions people have when they take Gaviscon and Disipal. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Gaviscon?

Gaviscon has active ingredients of aluminum hydroxide; magnesium trisilicate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 12,355 Gaviscon users. Check the latest studies of Gaviscon.

What is Disipal?

Disipal has active ingredients of orphenadrine hydrochloride. eHealthMe is studying from 219 Disipal users. Check the latest studies of Disipal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

14 people who take Gaviscon and Disipal together, and have interactions are studied.

What are the common drug interactions of Gaviscon and Disipal, by gender? *:

female:

Sudden death
Hallucination (an experience involving the perception of something not present)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Dyspnoea (difficult or laboured respiration)
Gastric ulcer (stomach ulcer)
Hepatic pain (pain in liver)
Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Nightmare (unpleasant dream)

male:

n/a

What are the common drug interactions of Gaviscon and Disipal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sudden death
Sudden cardiac death
Abdominal pain upper
Aggression
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anxiety
Arrhythmia (irregular heartbeat)
Dizziness
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)

30-39:

Hallucination (an experience involving the perception of something not present)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Dizziness
Dyspnoea (difficult or laboured respiration)
Hepatic pain (pain in liver)
Nightmare (unpleasant dream)
Oropharyngeal pain
Psychotic disorder
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 14 people, 100.00%
Psychotic Disorder: 6 people, 42.86%
Iron Deficiency Anaemia: 6 people, 42.86%
Gastric Ulcer (stomach ulcer): 6 people, 42.86%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 35.71%
Adverse Drug Reaction: 5 people, 35.71%

* Approximation only. Some reports may have incomplete information.

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