Paracetamol and Menstruation irregular - a phase IV clinical study of FDA data

Summary:

Menstruation irregular is reported as a side effect among people who take Paracetamol (acetaminophen), especially for people who are 40-49 old, have been taking the drug for < 1 month also take Pantoprazole, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Menstruation irregular when taking Paracetamol. It is created by eHealthMe based on reports of 114,713 people who have side effects when taking Paracetamol from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Menstruation irregular?

Menstruation irregular is found to be associated with 621 drugs and 912 conditions by eHealthMe. Check the latest studies of Menstruation irregular.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

114,713 people reported to have side effects when taking Paracetamol.
Among them, 50 people (0.04%) have Menstruation irregular.

Could Paracetamol cause Menstruation irregular?

Among these 50 people:

How long have people been on Paracetamol when they have Menstruation irregular? *

What is the age of people who have Menstruation irregular when taking Paracetamol? *

What are other drugs people take besides Paracetamol? *

What are other side effects people have besides Menstruation irregular? *

Fatigue (feeling of tiredness): 25 people, 50.00%
Weakness: 21 people, 42.00%
Joint Pain: 16 people, 32.00%
Back Pain: 15 people, 30.00%
Pain In Extremity: 15 people, 30.00%
Rashes (redness): 14 people, 28.00%
Nausea (feeling of having an urge to vomit): 14 people, 28.00%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 28.00%
Dyspnea (difficult or laboured breathing): 14 people, 28.00%
Chills (felling of cold): 13 people, 26.00%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 15 people, 30.00%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 9 people, 18.00%
Urinary Tract Infection: 8 people, 16.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 8 people, 16.00%
Borderline Personality Disorder: 8 people, 16.00%
Depression: 8 people, 16.00%
Epigastric Discomfort: 8 people, 16.00%
Gastric Ulcer (stomach ulcer): 8 people, 16.00%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 16.00%
Panic Disorder: 8 people, 16.00%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Menstruation irregular?

- Check whether Menstruation irregular is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paracetamol:

Paracetamol (115,650 reports)

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Menstruation irregular:

Menstruation irregular (621 drugs)

Browse all the conditions that are associated with Menstruation irregular:

Menstruation irregular (912 conditions)

Related publications that referenced our studies

Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.