Gemfibrozil and Asacol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gemfibrozil (gemfibrozil) and Asacol (mesalamine). Common drug interactions include acne among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Gemfibrozil and Asacol. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Gemfibrozil?
Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
32 people who take Gemfibrozil and Asacol together, and have interactions are studied.

What are the common drug interactions of Gemfibrozil and Asacol, by gender? *:
female:
- Acne (skin problems that cause pimples)
- Alopecia (absence of hair from areas of the body)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Disability
- Fall
- Tremor (trembling or shaking movements in one or more parts of your body)
- Weight increased
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
- Breast cancer
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
- Death
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Haematoma (collection of blood outside the blood vessels)
- Haemorrhage (bleeding)
What are the common drug interactions of Gemfibrozil and Asacol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Depression
- Fatigue (feeling of tiredness)
- Rhinorrhoea (watery mucus discharge from the nose)
- Sneezing
50-59:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Constipation
- Depression
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
60+:
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Breast cancer
- International normalised ratio increased
- Interstitial lung disease
- Metastasis (spreadable cancer to other organ from origin)
- Muscle haemorrhage (bleeding in muscle)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pain in extremity
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pruritus (severe itching of the skin)
What are the existing conditions these people have? *
- High Blood Pressure: 10 people, 31.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 28.12%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 21.88%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 21.88%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 15.62%
- Diabetes: 5 people, 15.62%
- Depression: 5 people, 15.62%
- Stress And Anxiety: 4 people, 12.50%
- Joint Pain: 3 people, 9.38%
- Diarrhea: 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
Do you take Gemfibrozil and Asacol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gemfibrozil (18,213 reports)
- Asacol (20,618 reports)
Browse all drug interactions of Gemfibrozil and Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gemfibrozil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemfibrozil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Asacol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on gemfibrozil and mesalamine (the active ingredients of Gemfibrozil and Asacol, respectively), and Gemfibrozil and Asacol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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