Gemzar and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gemzar (gemcitabine hydrochloride) and Codeine (codeine sulfate). Common drug interactions include asthenia among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Gemzar and Codeine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Gemzar?

Gemzar has active ingredients of gemcitabine hydrochloride. It is often used in pancreatic carcinoma. eHealthMe is studying from 20,315 Gemzar users. Check the latest studies of Gemzar.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.



On Jul, 16, 2026

12 people who take Gemzar and Codeine together, and have interactions are studied.

Gemzar and Codeine drug interactions.

What are the common drug interactions of Gemzar and Codeine, by gender? *:

female:

  1. Asthenia (weakness)
  2. Swelling face
  3. Abdominal discomfort
  4. Abdominal pain upper
  5. Abscess jaw (tooth abscess or root abscess)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Blood cholesterol increased
  8. Bone disorder
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)

male:

  1. Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Gemzar and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Fatigue (feeling of tiredness)
  2. Decreased appetite
  3. Depression
  4. Headache (pain in head)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pruritus (severe itching of the skin)
  7. Pyrexia (fever)
  8. Speech disorder
  9. Abasia (inability to walk)
  10. Agitation (state of anxiety or nervous excitement)

40-49:

  1. Facial pain
  2. Fall
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Foot deformity (functional disability of foot)
  5. Foot fracture
  6. Gait disturbance
  7. Gastroenteritis clostridial (inflammation of stomach and intestine clostridial)
  8. Gingival pain (gum pain)
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  10. Head injury

50-59:

  1. Asthenia (weakness)
  2. Compression fracture (fracture due to pressure caused by injury)
  3. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Enterocele (hernia of the intestine through the vagina)
  9. Facial pain
  10. Fall

60+:

  1. Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

  1. Depression: 6 people, 50.00%
  2. Stress And Anxiety: 5 people, 41.67%
  3. Breast Cancer: 5 people, 41.67%
  4. Metastases To Spine (cancer spreads to spine): 5 people, 41.67%
  5. Metastases To Bone (cancer spreads to bone): 5 people, 41.67%
  6. Breast Cancer Female: 2 people, 16.67%
  7. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 16.67%
  8. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 8.33%
  9. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 8.33%
  10. Diabetes: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Gemzar and Codeine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gemzar and Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemzar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gemzar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gemcitabine hydrochloride and codeine sulfate (the active ingredients of Gemzar and Codeine, respectively), and Gemzar and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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