Gemzar and Pradaxa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gemzar (gemcitabine hydrochloride) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include pancytopenia among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Gemzar and Pradaxa. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Gemzar?
Gemzar has active ingredients of gemcitabine hydrochloride. It is often used in pancreatic carcinoma. eHealthMe is studying from 20,315 Gemzar users. Check the latest studies of Gemzar.
What is Pradaxa?
Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.
19 people who take Gemzar and Pradaxa together, and have interactions are studied.

What are the common drug interactions of Gemzar and Pradaxa, by gender? *:
female:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Disease progression
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- General physical health deterioration (weak health status)
- Haemorrhagic anaemia (anaemia due to excessive bleeding)
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
- Mucosal inflammation (infection of mucous membrane)
- Platelet count decreased
male:
- Renal failure (kidney dysfunction)
- Alanine aminotransferase increased
- Cholecystitis (infection of gallbladder)
- Duodenitis (inflammation of the duodenum)
- Fatigue (feeling of tiredness)
- Gastritis (inflammation of stomach)
- Pain
- Ascites (accumulation of fluid in the abdominal cavity)
- Concomitant disease progression (progress in accompanying disease)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
What are the common drug interactions of Gemzar and Pradaxa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemorrhagic anaemia (anaemia due to excessive bleeding)
60+:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Renal failure (kidney dysfunction)
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Concomitant disease progression (progress in accompanying disease)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Gamma-glutamyltransferase increased
- Haemobilia (presence of blood in the biliary tract)
- Malignant neoplasm progression (cancer tumour came back)
- Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
What are the existing conditions these people have? *
- High Blood Pressure: 5 people, 26.32%
- Breast Cancer: 3 people, 15.79%
- Abdominal Pain: 2 people, 10.53%
- Diabetes: 2 people, 10.53%
- Adenocarcinoma Pancreas (cancer of pancreas): 2 people, 10.53%
- Pain: 2 people, 10.53%
- Neuropathy Peripheral (surface nerve damage): 2 people, 10.53%
- Nausea (feeling of having an urge to vomit): 2 people, 10.53%
- Cardiac Disorder: 2 people, 10.53%
- Cardiac Failure Chronic: 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Gemzar and Pradaxa?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gemzar and Pradaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gemzar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pradaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemzar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pradaxa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on gemcitabine hydrochloride and dabigatran etexilate mesylate (the active ingredients of Gemzar and Pradaxa, respectively), and Gemzar and Pradaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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