Gentamicin and Pentam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gentamicin (gentamicin sulfate) and Pentam (pentamidine isethionate). Common drug interactions include lung neoplasm among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Gentamicin and Pentam. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

What is Pentam?

Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.

On Jul, 12, 2026

45 people who take Gentamicin and Pentam together, and have interactions are studied.

Gentamicin and Pentam drug interactions.

What are the common drug interactions of Gentamicin and Pentam, by gender? *:

female:

Lung neoplasm (tumour of lung)
Neoplasm progression (growth of tumour)
Nephrogenic anaemia (anaemia due to kidney disease)
Neurilemmoma malignant (a cancer tumour that typically grows on the myelin sheath of nerves in the head or neck)
Neuroblastoma (a cancer that forms in your nerve tissue)
Pain in extremity
Pancreatitis (inflammation of pancreas)
Paraplegia (paralysis of the legs and lower body)
Platelet count decreased
Pneumatosis (air or gas in an abnormal location in the body)

male:

Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Febrile neutropenia (fever with reduced white blood cells)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Thrombocytopenia (decrease of platelets in blood)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Blood glucose increased
Bone marrow failure

What are the common drug interactions of Gentamicin and Pentam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pyrexia (fever)
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Pleural effusion (water on the lungs)
Septic shock (shock due to blood infection)
Tooth abscess (pus formation in tooth)
Cerebral haemorrhage (bleeding within the brain)

10-19:

Dyskinesia (abnormality or impairment of voluntary movement)
Fatigue (feeling of tiredness)
Fungal infection
General physical health deterioration (weak health status)
Haemorrhage (bleeding)
Hallucination (an experience involving the perception of something not present)
Hepatitis (inflammation of the liver)
Hypoglycaemia (deficiency of glucose in the bloodstream)
International normalised ratio increased
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

20-29:

Drug ineffective
Upper respiratory tract infection

30-39:

Ascites (accumulation of fluid in the abdominal cavity)
Budd chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
Pyrexia (fever)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dyspnoea (difficult or laboured respiration)
Fungal infection
Hepatic failure (liver failure)
Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
Hepatomegaly (abnormal enlargement of the liver)
Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)

40-49:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Blood alkaline phosphatase nos increased
Blood bilirubin increased
Chronic kidney disease
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhage intracranial (bleeding within the skull)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Acute myocardial infarction (acute heart attack)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dermatitis infected (inflammation of the skin due to infection)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 22.22%
Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 8 people, 17.78%
Rashes (redness): 5 people, 11.11%
Pain: 5 people, 11.11%
Constipation: 5 people, 11.11%
Sedation: 4 people, 8.89%
Neutropenic Colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition): 4 people, 8.89%
Insomnia (sleeplessness): 4 people, 8.89%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 8.89%
Hypervolaemia (abnormally increased volume of blood): 4 people, 8.89%

* Approximation only. Some reports may have incomplete information.

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