Lopurin and Hepatitis e - a phase IV clinical study of FDA data

Summary:

Hepatitis e is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Hepatitis e when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Hepatitis e?

Hepatitis e is found to be associated with 118 drugs and 181 conditions by eHealthMe. Check the latest studies of Hepatitis e.

On Jul, 12, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 23 people (0.01%) have Hepatitis e.

Among these 23 people:

How long have people been on Lopurin when they have Hepatitis e? *

What is the gender of people who have Hepatitis e when taking Lopurin? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Hepatitis e when taking Lopurin? *

What are other drugs people take besides Lopurin? *

What are other side effects people have besides Hepatitis e? *

Pneumonia: 7 people, 30.43%
Nasopharyngitis (inflammation of the nasopharynx): 6 people, 26.09%
General Physical Health Deterioration (weak health status): 6 people, 26.09%
Gamma-Glutamyltransferase Increased: 6 people, 26.09%
Dyspnea Exertional: 6 people, 26.09%
Dyspnea (difficult or laboured breathing): 6 people, 26.09%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 26.09%
Cough: 4 people, 17.39%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 3 people, 13.04%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 2 people, 8.70%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 34.78%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 6 people, 26.09%
Infection: 2 people, 8.70%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 8.70%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 8.70%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 4.35%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 4.35%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 4.35%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 4.35%
Malignant Melanoma (skin cancer rises from melancytes): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Hepatitis e?

- Check whether Hepatitis e is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Hepatitis e treatments and more:

Hepatitis e (1,871 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis e:

Hepatitis e (118 drugs)

Browse all the conditions that are associated with Hepatitis e:

Hepatitis e (181 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.