Genvoya and Gemfibrozil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Gemfibrozil (gemfibrozil). Common drug interactions include anhedonia among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Genvoya and Gemfibrozil. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Genvoya?
Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.
What is Gemfibrozil?
Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.
39 people who take Genvoya and Gemfibrozil together, and have interactions are studied.

What are the common drug interactions of Genvoya and Gemfibrozil, by gender? *:
female:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Depression
- Emotional distress
- Muscle mass
- Osteoporosis (bones weak and more likely to break)
- Pain
- Skeletal injury (bone and supporting muscle injury)
- Multiple fractures
male:
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Gait disturbance
- Mobility decreased (ability to move is reduced)
- Bone loss
- Dysstasia (difficulty in standing)
- Multiple fractures
- Osteonecrosis (death of bone)
- Osteoporosis (bones weak and more likely to break)
- Drug resistance (reduction in effectiveness of a drug)
What are the common drug interactions of Genvoya and Gemfibrozil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
- Depression
- Osteonecrosis (death of bone)
- Bone loss
- Fracture
40-49:
- Bone density decreased
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
- Blood creatinine increased
- Bone loss
- Decreased activity
50-59:
- Pain
- Osteopenia (a condition where bone mineral density is lower than normal)
- Bone density decreased
- Chronic kidney disease
- Ankle fracture
- Depression
- Mobility decreased (ability to move is reduced)
- Multiple fractures
- Tibia fracture (fracture of lower leg bone)
- Compression fracture (fracture due to pressure caused by injury)
60+:
- Memory impairment
- Nightmare (unpleasant dream)
- Pain
- Bone pain
- Drug ineffective
- Pyrexia (fever)
- Viral load increased
What are the existing conditions these people have? *
- Pain: 4 people, 10.26%
- Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 3 people, 7.69%
- Hypertriglyceridaemia (excess of triglycerides in the blood): 3 people, 7.69%
- Quit Smoking: 2 people, 5.13%
- Hypersensitivity: 2 people, 5.13%
- Dyslipidaemia (abnormal amount of lipids): 2 people, 5.13%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Genvoya and Gemfibrozil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Genvoya (13,538 reports)
- Gemfibrozil (18,213 reports)
Browse all drug interactions of Genvoya and Gemfibrozil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Genvoya:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gemfibrozil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Genvoya and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemfibrozil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate and gemfibrozil (the active ingredients of Genvoya and Gemfibrozil, respectively), and Genvoya and Gemfibrozil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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