Genvoya and Levaquin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Levaquin (levofloxacin). Common drug interactions include anhedonia among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Genvoya and Levaquin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Genvoya?
Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.
What is Levaquin?
Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.
31 people who take Genvoya and Levaquin together, and have interactions are studied.

What are the common drug interactions of Genvoya and Levaquin, by gender? *:
female:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Osteoporosis (bones weak and more likely to break)
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Chronic kidney disease
- Fracture
- Ankle fracture
male:
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Multiple fractures
- Foot fracture
- Gait disturbance
- Hand fracture
- Mobility decreased (ability to move is reduced)
- Renal failure (kidney dysfunction)
- Spinal compression fracture (fracture due to spinal compression on bone)
What are the common drug interactions of Genvoya and Levaquin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Back pain
- Blood urine present
- Decreased activity
- Depression
- Emotional distress
- Fear
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Chronic kidney disease
- Bone density decreased
- Dizziness
- Hand fracture
- Osteoporosis (bones weak and more likely to break)
- Tooth fracture
50-59:
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Quality of life decreased
- Bone density decreased
- Decreased activity
- Foot fracture
- Multiple fractures
60+:
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Dysstasia (difficulty in standing)
- Mobility decreased (ability to move is reduced)
- Osteoporosis (bones weak and more likely to break)
- Renal impairment (severely reduced kidney function)
- Anaemia (lack of blood)
- Blood creatinine increased
- Drug ineffective
- Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
What are the existing conditions these people have? *
- Viral Infection: 5 people, 16.13%
- Bacterial Infection: 5 people, 16.13%
- Depression: 5 people, 16.13%
- Fungal Infection: 5 people, 16.13%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 16.13%
- High Blood Pressure: 5 people, 16.13%
- Pain: 5 people, 16.13%
- Nausea (feeling of having an urge to vomit): 3 people, 9.68%
- Blood Testosterone Decreased: 3 people, 9.68%
- Diabetes: 3 people, 9.68%
* Approximation only. Some reports may have incomplete information.
Do you take Genvoya and Levaquin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Genvoya and Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Genvoya:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Genvoya and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levaquin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate and levofloxacin (the active ingredients of Genvoya and Levaquin, respectively), and Genvoya and Levaquin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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