Gilotrif and Furosemide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gilotrif (afatinib dimaleate) and Furosemide (furosemide). Common drug interactions include cheilitis among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Gilotrif and Furosemide. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

58 people who take Gilotrif and Furosemide together, and have interactions are studied.

Gilotrif and Furosemide drug interactions.

What are the common drug interactions of Gilotrif and Furosemide, by gender? *:

female:

Cheilitis (infection of lips)
Cough
Dry mouth
Dyspnoea (difficult or laboured respiration)
Gingival bleeding (bleeding gums)
Herpes virus infection
Immunodeficiency
Nail disorder (disease of nail)
Neck mass (mass in neck)
Oral mucosal erythema (redness of the mucous membrane of mouth)

male:

Decreased appetite
Diarrhoea
Diplopia (double vision)
Eating disorder
Flatulence (flatus expelled through the anus)
Gastric ulcer (stomach ulcer)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypophagia (reduced food intake)
Intestinal obstruction

What are the common drug interactions of Gilotrif and Furosemide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

40-49:

n/a

50-59:

Diarrhoea
Constipation
Dry eye (lack of adequate tears)
Dry skin
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Onychoclasis (breaking of the nails)
Oral herpes (viral infection of mouth)
Oropharyngeal pain
Photopsia (presence of perceived flashes of light)

60+:

Diarrhoea
Decreased appetite
Cough
Lip pain
Hypophagia (reduced food intake)
Pain in extremity
Abdominal distension
Abdominal pain
Diplopia (double vision)
Eating disorder

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 29 people, 50.00%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 11 people, 18.97%
High Blood Pressure: 11 people, 18.97%
Lung Neoplasm Malignant (cancer tumour of lung): 9 people, 15.52%
Diarrhea: 9 people, 15.52%
Constipation: 7 people, 12.07%
Cardiac Disorder: 5 people, 8.62%
Pre-Existing Disease: 4 people, 6.90%
Fever: 4 people, 6.90%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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