Gilotrif and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gilotrif (afatinib dimaleate) and Prednisolone (prednisolone). Common drug interactions include interstitial lung disease among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Gilotrif and Prednisolone. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

On Feb, 19, 2026

26 people who take Gilotrif and Prednisolone together, and have interactions are studied.

Gilotrif and Prednisolone drug interactions.

What are the common drug interactions of Gilotrif and Prednisolone, by gender? *:

female:

Interstitial lung disease
Death
Depression
Diarrhoea
Insomnia (sleeplessness)
Electrolyte imbalance
Nausea (feeling of having an urge to vomit)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Hemiplegia (paralysis of one side of the body)

male:

Diarrhoea
Interstitial lung disease
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Erythema multiforme (a type of hypersensitivity reaction)
Gastrointestinal erosion (gradual destruction of gastrointestinal tract because of the inflamed mucous membrane lining the stomach)

What are the common drug interactions of Gilotrif and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hemiplegia (paralysis of one side of the body)
Monoplegia (a paralysis of a single limb)
Strabismus (a disorder in which the two eyes do not line up in the same direction)

50-59:

Interstitial lung disease
Death
Depression
Insomnia (sleeplessness)
Diarrhoea
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Malignant neoplasm progression (cancer tumour came back)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)

60+:

Diarrhoea
Interstitial lung disease
Cerebral infarction (less blood supply to brain resulting tissue damage)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Hyperglycaemia (high blood sugar)
Malignant neoplasm progression (cancer tumour came back)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Abdominal pain
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 16 people, 61.54%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 6 people, 23.08%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 5 people, 19.23%
Interstitial Lung Disease: 5 people, 19.23%
Insomnia (sleeplessness): 4 people, 15.38%
Dyspnea (difficult or laboured breathing): 4 people, 15.38%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 11.54%
Diarrhea: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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