Ginseng and Metformin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ginseng (ginseng, american) and Metformin (metformin hydrochloride). Common drug interactions include malaise among females and cough among males.
The phase IV clinical study analyzes what interactions people have when they take Ginseng and Metformin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Ginseng?
Ginseng has active ingredients of ginseng, american. eHealthMe is studying from 446 Ginseng users. Check the latest studies of Ginseng.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.
33 people who take Ginseng and Metformin together, and have interactions are studied.

What are the common drug interactions of Ginseng and Metformin, by gender? *:
female:
- Malaise (a feeling of general discomfort or uneasiness)
- White blood cell count increased
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Fatigue (feeling of tiredness)
- Oedema (fluid collection in tissue)
- Peripheral swelling
- Pyrexia (fever)
- Tooth abscess (pus formation in tooth)
- Asthenia (weakness)
- Blood chloride decreased
male:
- Cough
- Hyperglycaemia (high blood sugar)
- Fatigue (feeling of tiredness)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Insomnia (sleeplessness)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Nasopharyngitis (inflammation of the nasopharynx)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
What are the common drug interactions of Ginseng and Metformin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
50-59:
- Decreased appetite
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Balance disorder
- Chronic kidney disease
- Drug ineffective
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
60+:
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Blood cholesterol increased
- Blood sodium decreased
- Blood urea increased
- Brain stem stroke (rapid loss of brain function due to disturbance in the blood supply to the brain)
- Calculus urinary (stone in urinary system)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Colitis (inflammation of colon)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 6 people, 18.18%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 12.12%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 9.09%
- Pain: 3 people, 9.09%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 6.06%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.06%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.06%
- Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 6.06%
- High Blood Cholesterol: 2 people, 6.06%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.06%
* Approximation only. Some reports may have incomplete information.
Do you take Ginseng and Metformin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ginseng and Metformin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ginseng:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Metformin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ginseng and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metformin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ginseng, american and metformin hydrochloride (the active ingredients of Ginseng and Metformin, respectively), and Ginseng and Metformin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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