Gleevec and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Abilify (aripiprazole). Common drug interactions include malaise among females and abnormal weight gain among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Abilify. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

On Jul, 22, 2026

24 people who take Gleevec and Abilify together, and have interactions are studied.

What are the common drug interactions of Gleevec and Abilify, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Splenomegaly (enlargement of spleen)
Fatigue (feeling of tiredness)
Infection
Muscle spasms (muscle contraction)
Abdominal pain
Headache (pain in head)
Abdominal pain upper
Dysstasia (difficulty in standing)

male:

Abnormal weight gain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Tremor (trembling or shaking movements in one or more parts of your body)
Bone density decreased
Sleep disorder
Weight decreased
Death
Anxiety
Chronic kidney disease
Emotional distress

What are the common drug interactions of Gleevec and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Weight decreased

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Malaise (a feeling of general discomfort or uneasiness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Infection
Splenomegaly (enlargement of spleen)
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Hepatic pain (pain in liver)
Muscle atrophy (a decrease in the mass of the muscle)
Muscle spasms (muscle contraction)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Fall
Humerus fracture (injury to the upper arm bone)
Chronic kidney disease
Emotional distress
Pain
Renal failure (kidney dysfunction)
Bone density decreased
Conjunctival haemorrhage (bleeding underneath the conjunctiva)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 8 people, 33.33%
High Blood Pressure: 5 people, 20.83%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 12.50%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 12.50%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 8.33%
Stress And Anxiety: 2 people, 8.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 8.33%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 8.33%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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