Gleevec and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Medrol (methylprednisolone). Common drug interactions include disorientation among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Medrol. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.

On Aug, 07, 2026

42 people who take Gleevec and Medrol together, and have interactions are studied.

What are the common drug interactions of Gleevec and Medrol, by gender? *:

female:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug ineffective
Drug toxicity
Eye swelling
Headache (pain in head)
Meningeal disorder (disease of meninges)
Metastases to liver (cancer spreads to liver)
Mitral valve incompetence (inefficient heart valve)
Nuclear magnetic resonance imaging brain
Red blood cell sedimentation rate increased

male:

Abdominal pain
Drug intolerance (drug sensitivity)
Respiratory tract infection
Weight decreased
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Myalgia (muscle pain)
Pain in extremity
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Acanthosis (thickening of the skin)

What are the common drug interactions of Gleevec and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Myalgia (muscle pain)
Pain in extremity

20-29:

n/a

30-39:

Angiopathy (generic term for a disease of the blood vessels)
Aortic arteriosclerosis (hardening of the aortic arteries)
Bone erosion
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
C-reactive protein increased
Cerebral disorder (brain disease)
Meningeal disorder (disease of meninges)
Mitral valve incompetence (inefficient heart valve)
Nuclear magnetic resonance imaging brain
Pain

40-49:

Splenic cyst (cyst on spleen or near by)
Surgery
Swelling face
Vomiting
Pyrexia (fever)
Weight decreased
Abdominal pain
Cachexia (loss of weight)
Decreased appetite
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)

50-59:

Oedema peripheral (superficial swelling)
Platelet count decreased
White blood cell count decreased
Mean platelet volume decreased (less than normal average size of platelet cells in blood)
Depression
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)

60+:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Acanthosis (thickening of the skin)
Coma (state of unconsciousness lasting more than six hours)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Herpes zoster
Malaise (a feeling of general discomfort or uneasiness)
Metastases to liver (cancer spreads to liver)
Pain
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 12 people, 28.57%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 11.90%
Gastrointestinal Stromal Tumor: 4 people, 9.52%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 4 people, 9.52%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 7.14%
Blood Immunoglobulin G Decreased: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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