Gleevec and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include decreased appetite among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Spiriva. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Jul, 15, 2026

68 people who take Gleevec and Spiriva together, and have interactions are studied.

What are the common drug interactions of Gleevec and Spiriva, by gender? *:

female:

Decreased appetite
Diarrhoea
Muscle tightness
Oedema peripheral (superficial swelling)
Pulmonary mass
Pyrexia (fever)
Eye haemorrhage (bleeding in the eye)
Rash
Abdominal pain
Anaemia (lack of blood)

male:

Dyspnoea (difficult or laboured respiration)
Pyrexia (fever)
Recurrent cancer (repeated cancer)
Vomiting
Weight decreased
Memory impairment
Sneezing
White blood cell count decreased
Diarrhoea
Blood alkaline phosphatase increased

What are the common drug interactions of Gleevec and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal hernia
Alopecia (absence of hair from areas of the body)
Coma (state of unconsciousness lasting more than six hours)
Death
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Iodine allergy
Renal failure (kidney dysfunction)
Vomiting

30-39:

n/a

40-49:

Death
Gastric cancer (stomach cancer)
Abnormal dreams
Arthralgia (joint pain)
Blood potassium decreased
Local swelling (swelling at the site of some application of substance or injury)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)

50-59:

Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Memory impairment
Recurrent cancer (repeated cancer)
Sneezing
Vomiting
Weight decreased
Blood alkaline phosphatase increased
Blood lactate dehydrogenase increased
Diarrhoea

60+:

Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Muscle spasms (muscle contraction)
Rash
Actinic keratosis (skin disease due to sun exposure)
Cardiac murmur (an heart sound in valve abnormality)
Death
Eye disorder
Eye swelling
Hyperkeratosis (thickening of the outer layer of the skin)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 29 people, 42.65%
Gastrointestinal Stromal Tumor: 8 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Gleevec and Spiriva?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously