Gleevec and Tapazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Tapazole (methimazole). Common drug interactions include astrocytoma among females.
The phase IV clinical study analyzes what interactions people have when they take Gleevec and Tapazole. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Tapazole?
Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.
15 people who take Gleevec and Tapazole together, and have interactions are studied.

What are the common drug interactions of Gleevec and Tapazole, by gender? *:
female:
- Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells)
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Mastocytosis (an excessive number of apparently normal mast cells in the skin and, occasionally, in other organs)
- Metastasis (spreadable cancer to other organ from origin)
- Mouth ulceration (mouth ulcers)
- Nasal septum deviation (deviated nasal septum)
- Oral disorder (mouth disease)
- Oral pain
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteomyelitis (infection of bone)
male:
n/a
What are the common drug interactions of Gleevec and Tapazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells)
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Mastocytosis (an excessive number of apparently normal mast cells in the skin and, occasionally, in other organs)
- Metastasis (spreadable cancer to other organ from origin)
- Mouth ulceration (mouth ulcers)
- Nasal septum deviation (deviated nasal septum)
- Oral disorder (mouth disease)
- Oral pain
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteomyelitis (infection of bone)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 14 people, 93.33%
- Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 13 people, 86.67%
- Pancreatic Carcinoma (pancreatic cancer): 1 person, 6.67%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and Tapazole?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gleevec and Tapazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tapazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gleevec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tapazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate and methimazole (the active ingredients of Gleevec and Tapazole, respectively), and Gleevec and Tapazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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