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Glimepiride and Avinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glimepiride (glimepiride) and Avinza (morphine sulfate). Common drug interactions include anxiety among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Glimepiride and Avinza. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Avinza?

Avinza has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 1,728 Avinza users. Check the latest studies of Avinza.

On Aug, 02, 2026

11 people who take Glimepiride and Avinza together, and have interactions are studied.

Glimepiride and Avinza drug interactions.

What are the common drug interactions of Glimepiride and Avinza, by gender? *:

female:

  1. Anxiety
  2. Depressed mood
  3. Diarrhoea
  4. Fear
  5. Hypokalaemia (low potassium)
  6. Joint dislocation (a joint position is changed from normal position)
  7. Sleep disorder
  8. Small intestinal obstruction (blockage in small intestine)
  9. Stress
  10. Arthropathy

male:

  1. Death
  2. Testicular atrophy (wasting of testes)

What are the common drug interactions of Glimepiride and Avinza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death
  2. Testicular atrophy (wasting of testes)

50-59:

  1. Intervertebral disc protrusion (spinal disc protrusion)
  2. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  3. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  4. Limb injury
  5. Nausea (feeling of having an urge to vomit)
  6. Vomiting
  7. Anxiety
  8. Depressed mood
  9. Diarrhoea
  10. Fear

60+:

  1. Bradycardia (abnormally slow heart action)
  2. Dehydration (dryness resulting from the removal of water)
  3. Hypotension (abnormally low blood pressure)
  4. Intervertebral disc protrusion (spinal disc protrusion)
  5. Nausea (feeling of having an urge to vomit)
  6. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  7. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  8. Vomiting

What are the existing conditions these people have? *

  1. Depression: 2 people, 18.18%
  2. High Blood Cholesterol: 1 person, 9.09%
  3. Blood Testosterone Decreased: 1 person, 9.09%
  4. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Glimepiride and Avinza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glimepiride and Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glimepiride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glimepiride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride and morphine sulfate (the active ingredients of Glimepiride and Avinza, respectively), and Glimepiride and Avinza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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