Glimepiride and Plegridy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glimepiride (glimepiride) and Plegridy (peginterferon beta-1a). Common drug interactions include fall among females and injection site erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Glimepiride and Plegridy. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.



On Jul, 12, 2026

20 people who take Glimepiride and Plegridy together, and have interactions are studied.

Glimepiride and Plegridy drug interactions.

What are the common drug interactions of Glimepiride and Plegridy, by gender? *:

female:

  1. Fall
  2. Injection site erythema (redness at injection site)
  3. Cellulitis (infection under the skin)
  4. Gait disturbance
  5. Infection
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  8. Blood magnesium decreased
  9. Blood potassium decreased
  10. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)

male:

  1. Injection site erythema (redness at injection site)
  2. Feeling hot
  3. Headache (pain in head)
  4. Influenza like illness
  5. Adverse reaction
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Rectal haemorrhage (bleeding from anus)
  9. Renal impairment (severely reduced kidney function)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Glimepiride and Plegridy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood glucose increased
  2. Injection site erythema (redness at injection site)
  3. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Visual impairment

50-59:

  1. Fall
  2. Cellulitis (infection under the skin)
  3. Gait disturbance
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Blood magnesium decreased
  6. Blood potassium decreased
  7. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Dizziness
  10. Feeling hot

60+:

  1. Feeling hot
  2. Headache (pain in head)
  3. Influenza like illness
  4. Concussion (short loss of normal brain function in response to a head injury)
  5. Depressed mood
  6. Ear infection
  7. Fall
  8. Nausea (feeling of having an urge to vomit)
  9. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 18 people, 90.00%
  2. Gait Disturbance: 3 people, 15.00%
  3. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Glimepiride and Plegridy?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glimepiride and Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glimepiride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glimepiride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plegridy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride and peginterferon beta-1a (the active ingredients of Glimepiride and Plegridy, respectively), and Glimepiride and Plegridy (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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