Glipizide and Aggrastat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glipizide (glipizide) and Aggrastat (tirofiban hydrochloride). Common drug interactions include haematocrit decreased among females and haematuria present among males.

The phase IV clinical study analyzes what interactions people have when they take Glipizide and Aggrastat. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Aggrastat?

Aggrastat has active ingredients of tirofiban hydrochloride. eHealthMe is studying from 3,696 Aggrastat users. Check the latest studies of Aggrastat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

14 people who take Glipizide and Aggrastat together, and have interactions are studied.

Glipizide and Aggrastat drug interactions.

What are the common drug interactions of Glipizide and Aggrastat, by gender? *:

female:

  1. Haematocrit decreased
  2. Haemoglobin decreased
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Haematoma (collection of blood outside the blood vessels)
  6. Haematuria present (presence of blood in urine due to trauma)
  7. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  8. Injection site haemorrhage (bleeding from injection site)
  9. Mitral valve incompetence (inefficient heart valve)
  10. Pulmonary oedema (fluid accumulation in the lungs)

male:

  1. Haematuria present (presence of blood in urine due to trauma)
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Sweating increased (excess sweating)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Pyrexia (fever)
  8. Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
  9. Anuria (failure of the kidneys to produce urine)
  10. Blood creatinine increased

What are the common drug interactions of Glipizide and Aggrastat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Haematuria present (presence of blood in urine due to trauma)
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Pyrexia (fever)
  4. Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
  5. Sweating increased (excess sweating)

60+:

  1. Haematocrit decreased
  2. Haemoglobin decreased
  3. Rigors (an episode of shaking or exaggerated shivering)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
  6. Anuria (failure of the kidneys to produce urine)
  7. Arterial disorder
  8. Blood creatinine increased
  9. Blood pressure decreased
  10. Cardiac disorder

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glipizide and Aggrastat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aggrastat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glipizide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aggrastat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glipizide and tirofiban hydrochloride (the active ingredients of Glipizide and Aggrastat, respectively), and Glipizide and Aggrastat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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