Glipizide and Folate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glipizide (glipizide) and Folate (folic acid). Common drug interactions include constipation among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Glipizide and Folate. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Glipizide?
Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.
What is Folate?
Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.
35 people who take Glipizide and Folate together, and have interactions are studied.

What are the common drug interactions of Glipizide and Folate, by gender? *:
female:
- Constipation
- Fall
- Muscle spasms (muscle contraction)
- Hypoaesthesia (reduced sense of touch or sensation)
- Muscular weakness (muscle weakness)
- Skeletal injury (bone and supporting muscle injury)
- Tension (the act or process of stretching something tight)
- Anaemia (lack of blood)
- Abdominal pain
- Acute myocardial infarction (acute heart attack)
male:
- Anxiety
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Lymphoma (cancer that begins in immune system cells)
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
- Nausea (feeling of having an urge to vomit)
- Pain
- Pneumonia viral
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Quality of life decreased
- Vertigo
What are the common drug interactions of Glipizide and Folate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abscess limb (limb infection)
- Anxiety
- Cellulitis (infection under the skin)
- Depression
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Groin abscess (pus in groin)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Perineal abscess
- Renal injury (kidney injury)
- Sepsis (a severe blood infection that can lead to organ failure and death)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Decreased activity
- Emotional distress
- Impaired work ability
- Pain
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Quality of life decreased
- Blood glucose decreased
60+:
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Acute hepatic failure
- Acute myocardial infarction (acute heart attack)
- Angioedema (rapid swelling of the dermis)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
- Cardiac failure congestive
- Cholecystitis infective (infection of gallbladder capable to infect other organs)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 5 people, 14.29%
- Type 2 Diabetes: 4 people, 11.43%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 11.43%
- High Blood Pressure: 4 people, 11.43%
- Stress And Anxiety: 3 people, 8.57%
- Pain: 3 people, 8.57%
- Insomnia (sleeplessness): 3 people, 8.57%
- High Blood Cholesterol: 3 people, 8.57%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.71%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Glipizide and Folate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Glipizide and Folate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glipizide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glipizide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Folate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on glipizide and folic acid (the active ingredients of Glipizide and Folate, respectively), and Glipizide and Folate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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