Zyloprim and Neupogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyloprim (allopurinol) and Neupogen (filgrastim). Common drug interactions include constipation among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Zyloprim and Neupogen. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Zyloprim?

Zyloprim has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 5,638 Zyloprim users. Check the latest studies of Zyloprim.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

On Jul, 08, 2026

44 people who take Zyloprim and Neupogen together, and have interactions are studied.

Zyloprim and Neupogen drug interactions.

What are the common drug interactions of Zyloprim and Neupogen, by gender? *:

female:

Constipation
Multiple myeloma (cancer of the plasma cells)
Oral pain
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood alkaline phosphatase increased

male:

Pleural effusion (water on the lungs)
Blood creatinine increased
Bone marrow failure
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypoxia (low oxygen in tissues)
Pericardial effusion (fluid around the heart)
Abdominal pain
Atelectasis (partial or complete collapse of the lung)
Cardiac failure congestive
Dry skin

What are the common drug interactions of Zyloprim and Neupogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)

20-29:

n/a

30-39:

n/a

40-49:

Hypertension (high blood pressure)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Blood alkaline phosphatase increased
Blood creatinine increased
Chest pain

50-59:

Dry skin
Dyspnoea (difficult or laboured respiration)
Heart rate increased
Insomnia (sleeplessness)
Klebsiella infection
Localised oedema (fluid retention in a particular part of the body)
Lymphocyte count increased
Mean cell volume increased (more than normal average red blood cell volume)
Mean platelet volume decreased (less than normal average size of platelet cells in blood)
Monocyte count increased

60+:

Aphasia (damage to the parts of the brain that control language)
Tremor (trembling or shaking movements in one or more parts of your body)
Pneumonia
Atelectasis (partial or complete collapse of the lung)
Constipation
Diarrhoea
Fatigue (feeling of tiredness)
Fluid overload (too much fluid in the blood)
Hypoxia (low oxygen in tissues)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 8 people, 18.18%
Nausea (feeling of having an urge to vomit): 8 people, 18.18%
Pain: 6 people, 13.64%
Nausea And Vomiting: 6 people, 13.64%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 13.64%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 11.36%
Stress And Anxiety: 5 people, 11.36%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.09%
Insomnia (sleeplessness): 4 people, 9.09%
Indigestion: 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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