Glucophage and Mesalamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glucophage (metformin hydrochloride) and Mesalamine (mesalamine). Common drug interactions include myopathy among females and escherichia urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Glucophage and Mesalamine. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

On Jul, 11, 2026

28 people who take Glucophage and Mesalamine together, and have interactions are studied.

Glucophage and Mesalamine drug interactions.

What are the common drug interactions of Glucophage and Mesalamine, by gender? *:

female:

Myopathy (a muscular disease in which the muscle fibres do not function)
Nasal polyps (masses that develop in the lining of the nose)
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Oedema (fluid collection in tissue)
Oral candidiasis (fungal infection of mouth)
Oropharyngeal pain
Pain in extremity
Panic attack

male:

Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Pneumonia
Blood glucose increased
Blood potassium decreased
Blood sodium decreased
Decreased appetite
Depressed mood
Depression
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Glucophage and Mesalamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Blood pressure increased
Dizziness
Drug hypersensitivity
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

Cough
Dizziness
Pyrexia (fever)
Viral infection

50-59:

Disease progression
Adverse event
Anal cancer
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Asthenia (weakness)
Blood glucose increased
Blood potassium decreased
Blood sodium decreased
Chest pain

60+:

Decreased appetite
Diarrhoea
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anaemia (lack of blood)
Animal scratch
Arthralgia (joint pain)
Back pain
Balance disorder
Bladder pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 13 people, 46.43%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 8 people, 28.57%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 25.00%
Pancreatic Carcinoma (pancreatic cancer): 3 people, 10.71%
Type 2 Diabetes: 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%
High Blood Cholesterol: 2 people, 7.14%
Gastric Disorder (disease of stomach): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Glucophage and Mesalamine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously