Glucophage and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glucophage (metformin hydrochloride) and Vimpat (lacosamide). Common drug interactions include blood iron decreased among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Glucophage and Vimpat. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

On Jul, 11, 2026

27 people who take Glucophage and Vimpat together, and have interactions are studied.

Glucophage and Vimpat drug interactions.

What are the common drug interactions of Glucophage and Vimpat, by gender? *:

female:

Blood iron decreased
Blood pressure increased
Blood sodium decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation
Cardiac failure congestive
Cardiac murmur (an heart sound in valve abnormality)
Cataract (clouding of the lens inside the eye)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Memory impairment
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Rash erythematous (redness of the skin)

What are the common drug interactions of Glucophage and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agitation (state of anxiety or nervous excitement)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Nausea (feeling of having an urge to vomit)
Vomiting

30-39:

Dizziness
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Dehydration (dryness resulting from the removal of water)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dysarthria (speech disorder)
Gait disturbance
Headache (pain in head)

50-59:

Asthenia (weakness)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diplopia (double vision)
Dysarthria (speech disorder)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)

60+:

Oedema peripheral (superficial swelling)
Depressed level of consciousness
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Pain
Peripheral coldness
Skin disorder (skin disease)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Hyperthermia (body temperature greatly above normal)
Lung disorder (lung disease)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 37.04%
Type 2 Diabetes: 8 people, 29.63%
Pain: 8 people, 29.63%
Depression: 6 people, 22.22%
Stress And Anxiety: 5 people, 18.52%
Headache (pain in head): 5 people, 18.52%
Nausea (feeling of having an urge to vomit): 4 people, 14.81%
Insomnia (sleeplessness): 4 people, 14.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.81%
High Blood Cholesterol: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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