Glyburide and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyburide (glyburide) and Divalproex (divalproex sodium). Common drug interactions include pain in extremity among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Glyburide and Divalproex. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

On Jul, 17, 2026

67 people who take Glyburide and Divalproex together, and have interactions are studied.

Glyburide and Divalproex drug interactions.

What are the common drug interactions of Glyburide and Divalproex, by gender? *:

female:

Pain in extremity
Abnormal behaviour
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Crying
Diabetes mellitus insulin-dependent
Dyspnoea (difficult or laboured respiration)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypokalaemia (low potassium)

male:

Dyspnoea (difficult or laboured respiration)
Anxiety
Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Abscess (pus)
Actinomycosis (infection that causes sores, or abscesses)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Amyloidosis (a tumour within which amyloid is produced)

What are the common drug interactions of Glyburide and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Nausea (feeling of having an urge to vomit)
Vomiting

40-49:

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal tenderness
Abnormal behaviour
Acute respiratory distress syndrome
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthenia (weakness)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)

50-59:

Agitation (state of anxiety or nervous excitement)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Amyloidosis (a tumour within which amyloid is produced)
Anaemia (lack of blood)
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Balance disorder
Chest discomfort
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Actinomycosis (infection that causes sores, or abscesses)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Amyloidosis (a tumour within which amyloid is produced)
Anxiety
Arthralgia (joint pain)
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 11.94%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 8.96%
High Blood Cholesterol: 5 people, 7.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.46%
Depression: 5 people, 7.46%
Stress And Anxiety: 4 people, 5.97%
Pain: 4 people, 5.97%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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