Glycopyrrolate and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glycopyrrolate (glycopyrrolate) and Digoxin (digoxin). Common drug interactions include orthostatic hypertension among females and dilatation ventricular among males.

The phase IV clinical study analyzes what interactions people have when they take Glycopyrrolate and Digoxin. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Glycopyrrolate?

Glycopyrrolate has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 5,599 Glycopyrrolate users. Check the latest studies of Glycopyrrolate.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 08, 2026

81 people who take Glycopyrrolate and Digoxin together, and have interactions are studied.

Glycopyrrolate and Digoxin drug interactions.

What are the common drug interactions of Glycopyrrolate and Digoxin, by gender? *:

female:

Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)
Pneumonia
Urinary tract infection
Cardiac arrest
Pleural effusion (water on the lungs)
Tricuspid valve incompetence (inefficient heart valve)
Respiratory failure (inadequate gas exchange by the respiratory system)
Atelectasis (partial or complete collapse of the lung)
Diarrhoea
Lymphadenopathy (disease or enlargement of lymph nodes)

male:

Dilatation ventricular
Acute myocardial infarction (acute heart attack)
Loss of consciousness
Mitral valve calcification (calcium deposit in mitral valve)
Mitral valve incompetence (inefficient heart valve)
Arthralgia (joint pain)
Cardiomegaly (increased size of heart than normal)
Cerebral atrophy (decrement in size of brain)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased appetite

What are the common drug interactions of Glycopyrrolate and Digoxin, by age (0-1 to 60+)? *:

0-1:

Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Haematochezia (passage of stools containing blood)
Left ventricular failure (left ventricle fails to contract forcefully)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Neurological symptom (symptoms of nervous system disease)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Reaction to drug excipients
Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection
Ventricular extrasystoles (premature cardiac contraction)

2-9:

Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Increased upper airway secretion
Oxygen saturation decreased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hospitalisation
Pulmonary congestion (congestion in the lungs)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Viral infection

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Dyspnoea (difficult or laboured respiration)
Extrasystoles

40-49:

n/a

50-59:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriovenous fistula site complication
Atelectasis (partial or complete collapse of the lung)
Bone disorder
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac arrest
Cardiac disorder
Cardiac failure congestive

60+:

Dyspnoea (difficult or laboured respiration)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac failure congestive
Weight decreased
Hypotension (abnormally low blood pressure)
Constipation
Respiratory failure (inadequate gas exchange by the respiratory system)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Ventricular fibrillation (abnormally irregular heart rhythm)
Diarrhoea

What are the existing conditions these people have? *

Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 16 people, 19.75%
Multiple Myeloma (cancer of the plasma cells): 13 people, 16.05%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 10 people, 12.35%
Arrhythmias (irregular heartbeat): 9 people, 11.11%
Pain: 6 people, 7.41%
Asthma: 6 people, 7.41%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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