Arimidex and Necrosis - a phase IV clinical study of FDA data
Summary:
Necrosis is reported as a side effect among people who take Arimidex (anastrozole), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Zometa, and have Bone lesion.
The phase IV clinical study analyzes which people have Necrosis when taking Arimidex. It is created by eHealthMe based on reports of 21,680 people who have side effects when taking Arimidex from the FDA, and is updated regularly.
What is Arimidex?
Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.
What is Necrosis?
Necrosis (the death of body tissue) is found to be associated with 764 drugs and 969 conditions by eHealthMe. Check the latest studies of Necrosis.
21,680 people reported to have side effects when taking Arimidex.
Among them, 24 people (0.11%) have Necrosis.

Among these 24 people:
How long have people been on Arimidex when they have Necrosis? *
- < 1 month: 33.33 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 66.67 %
- 10+ years: 0.0 %
What is the gender of people who have Necrosis when taking Arimidex? *
- female: 87.5 %
- male: 12.5 %
What is the age of people who have Necrosis when taking Arimidex? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 71.43 %
- 50-59: 21.43 %
- 60+: 7.14 %
What are other drugs people take besides Arimidex? *
- Zometa: 10 people, 41.67%
- Aredia: 9 people, 37.50%
- Fosamax: 9 people, 37.50%
- Taxotere: 9 people, 37.50%
- Lortab: 8 people, 33.33%
- Celebrex: 8 people, 33.33%
- Neurontin: 8 people, 33.33%
- Keflex: 8 people, 33.33%
- Tamoxifen Citrate: 8 people, 33.33%
- Femara: 8 people, 33.33%
What are other side effects people have besides Necrosis? *
- Pain: 17 people, 70.83%
- Stress And Anxiety: 16 people, 66.67%
- Anaemia (lack of blood): 16 people, 66.67%
- Rashes (redness): 15 people, 62.50%
- General Physical Health Deterioration (weak health status): 15 people, 62.50%
- Impaired Healing: 14 people, 58.33%
- Hot Flush (sudden feelings of heat): 14 people, 58.33%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 14 people, 58.33%
- Decreased Interest: 14 people, 58.33%
- Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 54.17%
What are the existing conditions these people have? *
- Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 7 people, 29.17%
- High Blood Pressure: 2 people, 8.33%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.17%
- Hyperthyroidism (over activity of the thyroid gland): 1 person, 4.17%
- Bone Density Decreased: 1 person, 4.17%
- Breast Cancer Metastatic: 1 person, 4.17%
- Gastritis (inflammation of stomach): 1 person, 4.17%
- Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 4.17%
- High Blood Cholesterol: 1 person, 4.17%
- Menopause (end of monthly cycles in women): 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Arimidex and have Necrosis?
- Check whether Necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Arimidex:
- Arimidex (22,642 reports)
Necrosis treatments and more:
- Necrosis (8,274 reports)
How severe was Necrosis and when was it recovered:
Expand to all the drugs that have ingredients of anastrozole:
- Necrosis and drugs with ingredients of anastrozole (38 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Arimidex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Necrosis:
- Necrosis (764 drugs)
Browse all the conditions that are associated with Necrosis:
- Necrosis (969 conditions)
Related publications that referenced our studies
- Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
- Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on anastrozole (the active ingredients of Arimidex) and Arimidex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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