Glycopyrrolate and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glycopyrrolate (glycopyrrolate) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include pain among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Glycopyrrolate and Hydrocodone. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Glycopyrrolate?

Glycopyrrolate has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 5,599 Glycopyrrolate users. Check the latest studies of Glycopyrrolate.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.



On Jul, 14, 2026

16 people who take Glycopyrrolate and Hydrocodone together, and have interactions are studied.

Glycopyrrolate and Hydrocodone drug interactions.

What are the common drug interactions of Glycopyrrolate and Hydrocodone, by gender? *:

female:

  1. Pain
  2. Asthenia (weakness)
  3. Back disorder
  4. Dizziness
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Nausea (feeling of having an urge to vomit)
  8. Arthralgia (joint pain)
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Respiratory distress (difficulty in breathing)
  3. Oedema peripheral (superficial swelling)
  4. Peripheral swelling
  5. Swelling
  6. Weight increased
  7. Upper respiratory tract infection
  8. Back pain
  9. Blood pressure fluctuation
  10. Blood pressure systolic decreased

What are the common drug interactions of Glycopyrrolate and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Respiratory distress (difficulty in breathing)
  3. Upper respiratory tract infection

50-59:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Back disorder
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Dizziness
  7. Dry eye (lack of adequate tears)
  8. Dry mouth
  9. Fall
  10. Fatigue (feeling of tiredness)

60+:

  1. Dizziness
  2. Fatigue (feeling of tiredness)
  3. Cellulitis (infection under the skin)
  4. Depression
  5. Drug hypersensitivity
  6. Dyspnoea (difficult or laboured respiration)
  7. Genital infection
  8. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  9. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  10. Joint swelling

What are the existing conditions these people have? *

  1. Pain: 4 people, 25.00%
  2. High Blood Pressure: 4 people, 25.00%
  3. Lichen Myxoedematosus (deposition of acid mucopolysaccharides in the skin): 4 people, 25.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
  5. Diabetes: 3 people, 18.75%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 18.75%
  7. Muscle Spasms (muscle contraction): 3 people, 18.75%
  8. Cough: 3 people, 18.75%
  9. Nausea (feeling of having an urge to vomit): 2 people, 12.50%
  10. Infection: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glycopyrrolate and Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glycopyrrolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glycopyrrolate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate and hydrocodone bitartrate; ibuprofen (the active ingredients of Glycopyrrolate and Hydrocodone, respectively), and Glycopyrrolate and Hydrocodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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