Grape and Coumadin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Grape (grape) and Coumadin (warfarin sodium). Common drug interactions include neuropathy peripheral among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Grape and Coumadin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Grape?

Grape has active ingredients of grape. eHealthMe is studying from 1,229 Grape users. Check the latest studies of Grape.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

17 people who take Grape and Coumadin together, and have interactions are studied.

Grape and Coumadin drug interactions.

What are the common drug interactions of Grape and Coumadin, by gender? *:

female:

  1. Neuropathy peripheral (surface nerve damage)
  2. Pain in extremity
  3. Visual impairment
  4. Insomnia (sleeplessness)
  5. Dizziness
  6. Abdominal pain
  7. Actinic keratosis (skin disease due to sun exposure)
  8. Adhesion
  9. Amaurosis fugax (painless transient monocular visual loss)
  10. Angiolipoma (a benign tumour composed chiefly of fat cells)

male:

  1. Abdominal pain
  2. Aspartate aminotransferase increased
  3. Abdominal discomfort
  4. Abdominal distension
  5. Abdominal pain upper
  6. Actinic keratosis (skin disease due to sun exposure)
  7. Adhesion
  8. Adverse drug reaction
  9. Alanine aminotransferase increased
  10. Amaurosis fugax (painless transient monocular visual loss)

What are the common drug interactions of Grape and Coumadin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Actinic keratosis (skin disease due to sun exposure)
  3. Adhesion
  4. Amaurosis fugax (painless transient monocular visual loss)
  5. Angiolipoma (a benign tumour composed chiefly of fat cells)
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Antiphospholipid antibodies positive
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Aspartate aminotransferase increased

50-59:

  1. Disturbance in attention
  2. Dry skin
  3. Dyspepsia (indigestion)
  4. Dyspnoea (difficult or laboured respiration)
  5. Ejection fraction decreased (systolic heart failure)
  6. Epistaxis (bleed from the nose)
  7. Erythema (redness of the skin)
  8. Extrasystoles
  9. Fatigue (feeling of tiredness)
  10. Feeling hot

60+:

  1. Diarrhoea
  2. Dizziness
  3. Myalgia (muscle pain)
  4. Pain in extremity
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Abdominal discomfort
  7. Abdominal distension
  8. Abdominal pain upper
  9. Actinic keratosis (skin disease due to sun exposure)
  10. Adhesion

What are the existing conditions these people have? *

  1. Pain: 5 people, 29.41%
  2. Oedema (fluid collection in tissue): 5 people, 29.41%
  3. Hypomania (a mild form of mania, marked by elation and hyperactivity): 5 people, 29.41%
  4. Protein S Deficiency: 4 people, 23.53%
  5. Breast Cancer: 3 people, 17.65%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.76%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 5.88%
  8. Prostate Cancer Metastatic: 1 person, 5.88%
  9. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.88%
  10. Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Grape and Coumadin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Grape and Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Grape:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Grape and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coumadin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on grape and warfarin sodium (the active ingredients of Grape and Coumadin, respectively), and Grape and Coumadin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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