Gravol and Cisplatin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gravol (dimenhydrinate) and Cisplatin (cisplatin). Common drug interactions include bronchopleural fistula among females and dehydration among males.
The phase IV clinical study analyzes what interactions people have when they take Gravol and Cisplatin. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Gravol?
Gravol has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 7,192 Gravol users. Check the latest studies of Gravol.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
29 people who take Gravol and Cisplatin together, and have interactions are studied.

What are the common drug interactions of Gravol and Cisplatin, by gender? *:
female:
- Bronchopleural fistula
- Dyspnoea (difficult or laboured respiration)
- Cough
- Emotional distress
- Erythema (redness of the skin)
- Face oedema (swelling of face)
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Rash macular (small, flat red spots)
- Agitation (state of anxiety or nervous excitement)
- Confusion
male:
- Dehydration (dryness resulting from the removal of water)
- Malignant neoplasm progression (cancer tumour came back)
- Haemoglobin decreased
- Herpes virus infection
- Neutropenia (an abnormally low number of neutrophils)
- Platelet count decreased
- Throat irritation
- Urinary tract infection
- Weight decreased
- Caecitis (inflammation of the cecum)
What are the common drug interactions of Gravol and Cisplatin, by age (0-1 to 60+)? *:
0-1:
- Cough
- Nasopharyngitis (inflammation of the nasopharynx)
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
2-9:
- Caecitis (inflammation of the cecum)
- Flatulence (flatus expelled through the anus)
- Neutropenia (an abnormally low number of neutrophils)
- Pneumatosis (air or gas in an abnormal location in the body)
10-19:
- Cough
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Erythema (redness of the skin)
- Face oedema (swelling of face)
- Rash macular (small, flat red spots)
20-29:
n/a
30-39:
- Bronchopleural fistula
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Metastases to bone (cancer spreads to bone)
- Tumour necrosis (death of tumour tissues)
- Haemoglobin decreased
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Oesophagitis (inflammation of oesophagus)
- Pneumonia
- Pulmonary cavitation (cavity in the lung)
40-49:
- Abdominal pain lower
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Back pain
- Claustrophobia (fear of having no escape and being closed in small spaces)
- Dehydration (dryness resulting from the removal of water)
- Febrile neutropenia (fever with reduced white blood cells)
- Intestinal perforation (complete penetration of the wall of the intestine)
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Stomatitis (inflammation of mucous membrane of mouth)
50-59:
- Dehydration (dryness resulting from the removal of water)
- Malignant neoplasm progression (cancer tumour came back)
- Renal failure acute (rapid kidney dysfunction)
- Respiratory tract infection
- Ascites (accumulation of fluid in the abdominal cavity)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Hypokalaemia (low potassium)
- Agitation (state of anxiety or nervous excitement)
- Confusion
60+:
- Urinary tract infection
- Cardiac arrest
- Pupil fixed
- Salivary hypersecretion (excess saliva secretion)
- Sudden death unexplained
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Dyspnoea (difficult or laboured respiration)
- Enterocolitis infectious
- Gasping (laboured breathing)
- Hyperkalaemia (damage to or disease of the kidney)
What are the existing conditions these people have? *
- Pain: 9 people, 31.03%
- Nausea And Vomiting: 8 people, 27.59%
- Gastric Cancer (stomach cancer): 7 people, 24.14%
- Lung Cancer - Non-Small Cell (lung cancer): 4 people, 13.79%
- Neoplasm Malignant (cancer tumour): 3 people, 10.34%
- Constipation: 3 people, 10.34%
- Non-Small Cell Lung Cancer Stage Iii: 2 people, 6.90%
- Neuroblastoma (a cancer that forms in your nerve tissue): 2 people, 6.90%
- Metastases To Bone (cancer spreads to bone): 2 people, 6.90%
- Cough: 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Gravol and Cisplatin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gravol and Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gravol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gravol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on dimenhydrinate and cisplatin (the active ingredients of Gravol and Cisplatin, respectively), and Gravol and Cisplatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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