Gravol and Detrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gravol (dimenhydrinate) and Detrol (tolterodine tartrate). Common drug interactions include renal impairment among females and gastritis erosive among males.

The phase IV clinical study analyzes what interactions people have when they take Gravol and Detrol. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Gravol?

Gravol has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 7,192 Gravol users. Check the latest studies of Gravol.

What is Detrol?

Detrol has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 28,669 Detrol users. Check the latest studies of Detrol.

On Aug, 08, 2026

28 people who take Gravol and Detrol together, and have interactions are studied.

What are the common drug interactions of Gravol and Detrol, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Tenderness (pain or discomfort when an affected area is touched)
Blood creatine increased
Death
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Feeling of body temperature change
Gingival swelling (gums swelling)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Chest discomfort
Lymphocyte count decreased
Malaise (a feeling of general discomfort or uneasiness)
Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
Mean cell volume increased (more than normal average red blood cell volume)
Micturition urgency (urgency to pass the urine)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Night sweats (sweating in night)

What are the common drug interactions of Gravol and Detrol, by age (0-1 to 60+)? *:

0-1:

Abdominal discomfort
Abdominal distension
Abdominal pain
Abdominal pain lower
Abdominal pain upper
Arthralgia (joint pain)
Back pain
Bladder pain
Blood glucose decreased
Blood glucose increased

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest discomfort
Cough
Dysgeusia (disorder of the sense of taste)
Epigastric discomfort
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Gamma-glutamyltransferase decreased
Headache (pain in head)
Lymphocyte count decreased

40-49:

Asthenia (weakness)
Aura
Balance disorder
Cough
Culture urine positive
Dysstasia (difficulty in standing)
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Haemoglobin increased
Hypertension (high blood pressure)

50-59:

Arthralgia (joint pain)
Back pain
Blood glucose decreased
Blood insulin decreased
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Pruritus (severe itching of the skin)
Dysphonia (speech disorder attributable to a disorder of phonation)
Feeling of body temperature change
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Palpitations (feelings or sensations that your heart is pounding or racing)
Throat irritation
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)

What are the existing conditions these people have? *

Primary Immunodeficiency Syndrome: 10 people, 35.71%
Hypersensitivity: 3 people, 10.71%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 7.14%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.14%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 7.14%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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