Guaifenesin and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Guaifenesin (guaifenesin) and Bumex (bumetanide). Common drug interactions include nausea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Guaifenesin and Bumex. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

On Jul, 13, 2026

82 people who take Guaifenesin and Bumex together, and have interactions are studied.

Guaifenesin and Bumex drug interactions.

What are the common drug interactions of Guaifenesin and Bumex, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Productive cough
Vomiting
Blood potassium decreased
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Asthma
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Wheezing (a high-pitched whistling sound made while you breath)

male:

Chronic kidney disease
Cardiac failure congestive
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Fluid overload (too much fluid in the blood)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Guaifenesin and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Aspergillosis (an infection caused by a fungus called aspergillus)
Febrile neutropenia (fever with reduced white blood cells)
Immunosuppression
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

20-29:

Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cholecystitis (infection of gallbladder)
Hypertension (high blood pressure)
Influenza like illness
Insomnia (sleeplessness)
Presyncope

30-39:

n/a

40-49:

Depression
Pyrexia (fever)
Respiratory distress (difficulty in breathing)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fungaemia (fungi circulate in the blood)
Hemiparesis (weakness on one side of the body)
Locked-in syndrome (a condition in which a patient is aware and awake but cannot move or communicate verbally due to complete paralysis)
Respiratory failure (inadequate gas exchange by the respiratory system)
Anxiety
Back pain

50-59:

Blood potassium decreased
Blood sodium decreased
Chest pain
Dizziness
Electrocardiogram qt prolonged
Headache (pain in head)
Hypoxia (low oxygen in tissues)
Oxygen saturation decreased
Asthenia (weakness)
Abdominal pain

60+:

Renal failure (kidney dysfunction)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Weight fluctuation
Weight increased
Abdominal discomfort
Abdominal distension
Oedema peripheral (superficial swelling)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Pain: 17 people, 20.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 19.51%
High Blood Pressure: 11 people, 13.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 10 people, 12.20%
Gout (uric acid crystals building up in the body): 8 people, 9.76%
Constipation: 8 people, 9.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 9.76%
Thyroid Diseases: 7 people, 8.54%
Thrombosis (formation of a blood clot inside a blood vessel): 7 people, 8.54%
Diabetes: 7 people, 8.54%

* Approximation only. Some reports may have incomplete information.

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