Prilosec and Lambert-eaton syndrome - a phase IV clinical study of FDA data

Summary:

Lambert-eaton syndrome is reported as a side effect among people who take Prilosec (omeprazole), especially for people who are female, 60+ old, also take Lasix, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Lambert-eaton syndrome when taking Prilosec. It is created by eHealthMe based on reports of 171,578 people who have side effects when taking Prilosec from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Lambert-eaton syndrome?

Lambert-eaton syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body) is found to be associated with 181 drugs and 302 conditions by eHealthMe. Check the latest studies of Lambert-eaton syndrome.

On Jul, 13, 2026

171,578 people reported to have side effects when taking Prilosec.
Among them, 30 people (0.02%) have Lambert-eaton syndrome.

Could Prilosec cause Lambert-eaton syndrome?

Among these 30 people:

What is the gender of people who have Lambert-eaton syndrome when taking Prilosec? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Lambert-eaton syndrome when taking Prilosec? *

What are other drugs people take besides Prilosec? *

What are other side effects people have besides Lambert-eaton syndrome? *

Weakness: 11 people, 36.67%
Back Pain: 6 people, 20.00%
Nausea (feeling of having an urge to vomit): 6 people, 20.00%
Myopathy (a muscular disease in which the muscle fibres do not function): 5 people, 16.67%
Weight Increased: 4 people, 13.33%
Muscle Aches (muscle pain): 4 people, 13.33%
Confusional State: 3 people, 10.00%
Weight Decreased: 3 people, 10.00%
Constipation: 3 people, 10.00%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 3 people, 10.00%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 2 people, 6.67%
Stress And Anxiety: 1 person, 3.33%
Sleep Disorder: 1 person, 3.33%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 3.33%
Nicotine Dependence: 1 person, 3.33%
Nausea And Vomiting: 1 person, 3.33%
Nausea (feeling of having an urge to vomit): 1 person, 3.33%
Lung Squamous Cell Carcinoma Stage Iii (lung cancer has spread to lymph nodes on the same side of the chest as the tumour. the lymph nodes with cancer are near the sternum (chest bone) or where the bronchus enters the lung): 1 person, 3.33%
Hyperacidity: 1 person, 3.33%
Constipation: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and have Lambert-eaton syndrome?

- Check whether Lambert-eaton syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prilosec:

Prilosec (175,285 reports)

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lambert-eaton syndrome:

Lambert-eaton syndrome (181 drugs)

Browse all the conditions that are associated with Lambert-eaton syndrome:

Lambert-eaton syndrome (302 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.