Defitelio and Ceftazidime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Defitelio (defibrotide sodium) and Ceftazidime (ceftazidime). Common drug interactions include acute respiratory distress syndrome among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Defitelio and Ceftazidime. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Defitelio?

Defitelio has active ingredients of defibrotide sodium. eHealthMe is studying from 4,343 Defitelio users. Check the latest studies of Defitelio.

What is Ceftazidime?

Ceftazidime has active ingredients of ceftazidime. eHealthMe is studying from 10,327 Ceftazidime users. Check the latest studies of Ceftazidime.

On Jul, 13, 2026

23 people who take Defitelio and Ceftazidime together, and have interactions are studied.

Defitelio and Ceftazidime drug interactions.

What are the common drug interactions of Defitelio and Ceftazidime, by gender? *:

female:

Acute respiratory distress syndrome
Colitis (inflammation of colon)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Drug ineffective
Gastritis (inflammation of stomach)
Melaena (the passage of black, tarry stools)
Overdose
Pericardial effusion (fluid around the heart)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

male:

Coma (state of unconsciousness lasting more than six hours)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Cerebral haemorrhage (bleeding within the brain)
Chills (felling of cold)
Hyperthermia (body temperature greatly above normal)
Intestinal haemorrhage (bleeding from intestine)
Pleural effusion (water on the lungs)
Pulmonary mycosis (lung infection caused by yeast-like fungi)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Defitelio and Ceftazidime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Respiratory failure (inadequate gas exchange by the respiratory system)
Respiratory tract haemorrhage (respiratory tract bleeding)
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombocytopenia (decrease of platelets in blood)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Acute respiratory distress syndrome
Acute respiratory failure
Cerebral haemorrhage (bleeding within the brain)
Colitis (inflammation of colon)
Gastritis (inflammation of stomach)

10-19:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Drug ineffective
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

20-29:

n/a

30-39:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Chills (felling of cold)
Hyperthermia (body temperature greatly above normal)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)

40-49:

n/a

50-59:

n/a

60+:

Pleural effusion (water on the lungs)
Venoocclusive disease (small veins in the liver are obstructed)

What are the existing conditions these people have? *

Venoocclusive Disease (small veins in the liver are obstructed): 13 people, 56.52%
Infection: 4 people, 17.39%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 17.39%
Cytomegalovirus Infection: 4 people, 17.39%
Pain: 3 people, 13.04%
Oedema (fluid collection in tissue): 3 people, 13.04%
Fever: 3 people, 13.04%
Stress And Anxiety: 2 people, 8.70%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 8.70%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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