Guaifenesin and Lisinopril and hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Guaifenesin (guaifenesin) and Lisinopril and hydrochlorothiazide (hydrochlorothiazide; lisinopril). Common drug interactions include wrist fracture among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Guaifenesin and Lisinopril and hydrochlorothiazide. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

What is Lisinopril and hydrochlorothiazide?

Lisinopril and hydrochlorothiazide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 10,259 Lisinopril and hydrochlorothiazide users. Check the latest studies of Lisinopril and hydrochlorothiazide.



On Jul, 07, 2026

32 people who take Guaifenesin and Lisinopril and hydrochlorothiazide together, and have interactions are studied.

Guaifenesin and Lisinopril and hydrochlorothiazide drug interactions.

What are the common drug interactions of Guaifenesin and Lisinopril And Hydrochlorothiazide, by gender? *:

female:

  1. Wrist fracture
  2. Dyspnoea (difficult or laboured respiration)
  3. Pain in extremity
  4. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  5. Adverse drug reaction
  6. Arthropathy
  7. Asthenia (weakness)
  8. Bradycardia (abnormally slow heart action)
  9. Chest pain
  10. Chronic kidney disease

male:

  1. Cardiac failure congestive
  2. Pneumonia
  3. Constipation
  4. Diabetic autonomic neuropathy (diabetes with nerve disorder, painful muscle wasting and weakness)
  5. Diarrhoea
  6. Drug ineffective
  7. Emotional disorder
  8. Emotional distress
  9. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  10. Fracture

What are the common drug interactions of Guaifenesin and Lisinopril And Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Cardiac failure congestive
  2. Pneumonia
  3. Chronic kidney disease
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Renal failure (kidney dysfunction)
  6. Renal tubular necrosis (death of kidney tubules)
  7. Cataract (clouding of the lens inside the eye)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Cellulitis (infection under the skin)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  3. Urinary tract infection
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Angioedema (rapid swelling of the dermis)
  6. Anxiety
  7. Arthralgia (joint pain)
  8. Blood creatinine increased
  9. Blood urea increased
  10. Cardiac failure congestive

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 18.75%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 18.75%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 12.50%
  5. Infection: 4 people, 12.50%
  6. High Blood Cholesterol: 3 people, 9.38%
  7. Urinary Tract Infection: 2 people, 6.25%
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 6.25%
  9. Burns Second Degree: 2 people, 6.25%
  10. Cardiac Disorder: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Guaifenesin and Lisinopril and hydrochlorothiazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Guaifenesin and Lisinopril and hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Guaifenesin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lisinopril and hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Guaifenesin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lisinopril and hydrochlorothiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin and hydrochlorothiazide; lisinopril (the active ingredients of Guaifenesin and Lisinopril and hydrochlorothiazide, respectively), and Guaifenesin and Lisinopril and hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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