Haldol and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Haldol (haloperidol) and Compazine (prochlorperazine maleate). Common drug interactions include fall among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Haldol and Compazine. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 27, 2026

67 people who take Haldol and Compazine together, and have interactions are studied.

What are the common drug interactions of Haldol and Compazine, by gender? *:

female:

Fall
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Metastases to central nervous system (cancer spreads to central nervous system)
Somnolence (a state of near-sleep, a strong desire for sleep)
Syncope (loss of consciousness with an inability to maintain postural tone)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased
Acute respiratory failure

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Disease progression
Pain
Procedural pain
Renal failure (kidney dysfunction)
Blood alkaline phosphatase increased
Blood creatinine increased
Blood magnesium decreased
Blood potassium decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Haldol and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blindness
Migraine (headache)
Rectal haemorrhage (bleeding from anus)
Suicidal ideation
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Drug hypersensitivity
Febrile neutropenia (fever with reduced white blood cells)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Infection

30-39:

Catheter site rash
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Right ventricular failure (right half of the heart fails to work)
Weight increased
Drug hypersensitivity

40-49:

Drug hypersensitivity
Fatigue (feeling of tiredness)
Acute respiratory failure
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood creatine increased
Cancer pain
Catheter site rash

50-59:

Mycotic allergy (fungal allergy)
Respiratory failure (inadequate gas exchange by the respiratory system)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Drug ineffective
Failure to thrive (inadequate weight gain and physical growth in children)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Parkinson's disease
Somnolence (a state of near-sleep, a strong desire for sleep)
Confusional state
Hepatic failure (liver failure)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Disease progression
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Drug hypersensitivity
Inflammation
Myositis (inflammation of the muscles)
Pain
Pleural effusion (water on the lungs)

What are the existing conditions these people have? *

Pain: 19 people, 28.36%
Nausea (feeling of having an urge to vomit): 18 people, 26.87%
Stress And Anxiety: 11 people, 16.42%
Insomnia (sleeplessness): 11 people, 16.42%
Constipation: 8 people, 11.94%
Migraine (headache): 8 people, 11.94%
Muscle Spasms (muscle contraction): 7 people, 10.45%
Sleep Disorder: 7 people, 10.45%
Neuralgia (pain in one or more nerves): 6 people, 8.96%
High Blood Cholesterol: 6 people, 8.96%

* Approximation only. Some reports may have incomplete information.

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