Haldol and Maxzide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Haldol (haloperidol) and Maxzide (hydrochlorothiazide; triamterene). Common drug interactions include diabetes mellitus among females and diabetes mellitus among males.
The phase IV clinical study analyzes what interactions people have when they take Haldol and Maxzide. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Haldol?
Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.
What is Maxzide?
Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.
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21 people who take Haldol and Maxzide together, and have interactions are studied.

What are the common drug interactions of Haldol and Maxzide, by gender? *:
female:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Type 2 diabetes mellitus
- Balance disorder
- Blood pressure decreased
- Cardiovascular insufficiency (inadequate functioning of heart)
- Excoriation (to tear or wear off the skin of)
- Fall
- Feelings of worthlessness
- Rash
- Respiratory rate increased (excess breathing rate/min)
male:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Weight increased
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Depression
- Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
- Diabetic gastropathy (gastric neuromuscular dysfunction in diabetes mellitus)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dyspnoea (difficult or laboured respiration)
- Ear pain
- Facial bones fracture (bone fracture of face)
What are the common drug interactions of Haldol and Maxzide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Type 2 diabetes mellitus
30-39:
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Type 1 diabetes mellitus
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Weight increased
- Type 2 diabetes mellitus
- Asthma
- Cardiac disorder
- Cellulitis (infection under the skin)
- Chest pain
40-49:
- Chronic kidney disease
- Death
- Diabetic coma
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Pancreatitis acute (sudden inflammation of pancreas)
- Type 2 diabetes mellitus
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bradyarrhythmia (heart slowness)
- Cardiac failure congestive
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
50-59:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Bipolar disorder (mood disorder)
- Delusion (a false belief or opinion)
- Diabetes mellitus inadequate control
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Mania (a state of abnormally elevated or irritable mood)
- Psychotic disorder
- Syphilis (sexually transmitted , chronic bacterial disease caused by the spirochete treponema pallidum)
- Type 2 diabetes mellitus
60+:
- Balance disorder
- Blood pressure decreased
- Abnormal behaviour
- Blood potassium decreased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Bradycardia (abnormally slow heart action)
- Cerebrovascular disorder (disease of brain)
- Death
- Depressed level of consciousness
What are the existing conditions these people have? *
- Depression: 9 people, 42.86%
- Bipolar Disorder (mood disorder): 6 people, 28.57%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 14.29%
- Orgasm Abnormal (abnormal sex satisfaction): 3 people, 14.29%
- Oedema (fluid collection in tissue): 3 people, 14.29%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 14.29%
- Malaria (a parasitic disease due to mosquito bite): 3 people, 14.29%
- Infection: 3 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Haldol and Maxzide?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Haldol and Maxzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Haldol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Maxzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Haldol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxzide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .
- Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on haloperidol and hydrochlorothiazide; triamterene (the active ingredients of Haldol and Maxzide, respectively), and Haldol and Maxzide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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