Haldol and Relafen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Haldol (haloperidol) and Relafen (nabumetone). Common drug interactions include retinal haemorrhage among females and type 2 diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Haldol and Relafen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.

What is Relafen?

Relafen has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 6,243 Relafen users. Check the latest studies of Relafen.



On Jul, 19, 2026

12 people who take Haldol and Relafen together, and have interactions are studied.

Haldol and Relafen drug interactions.

What are the common drug interactions of Haldol and Relafen, by gender? *:

female:

  1. Retinal haemorrhage (bleeding from retina)
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  3. Salivary gland mass
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Spinal column stenosis (narrowing of spinal column)
  6. Spinal osteoarthritis (joint cartilage loss in spine)
  7. Tricuspid valve incompetence (inefficient heart valve)
  8. Weight decreased
  9. Abdominal discomfort
  10. Abdominal distension

male:

  1. Type 2 diabetes mellitus
  2. Avulsion fracture (bone fracture)
  3. Jaundice cholestatic
  4. Joint sprain (an injury to joint surrounding flexible fibres)
  5. Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen)
  6. Metastases to liver (cancer spreads to liver)
  7. Metastases to peritoneum (cancer spreads to peritoneum)
  8. Nausea (feeling of having an urge to vomit)
  9. Overdose
  10. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)

What are the common drug interactions of Haldol and Relafen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Activities of daily living impaired
  4. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  5. Anxiety
  6. Asthenia (weakness)
  7. Bruxism (habitual grinding of the teeth, typically during sleep)
  8. Deformity (disfigurement)
  9. Depression
  10. Dyskinesia (abnormality or impairment of voluntary movement)

30-39:

  1. Avulsion fracture (bone fracture)
  2. Back pain
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Hyperglycaemia (high blood sugar)
  5. Intervertebral disc degeneration (spinal disc degeneration)
  6. Joint sprain (an injury to joint surrounding flexible fibres)
  7. Personality disorder
  8. Type 2 diabetes mellitus

40-49:

  1. Blood creatinine increased
  2. Nausea (feeling of having an urge to vomit)
  3. Neurological symptom (symptoms of nervous system disease)
  4. Overdose
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Vomiting
  8. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

  1. Tardive dyskinesia (a disorder that involves involuntary movements)
  2. Type 1 diabetes mellitus
  3. Type 2 diabetes mellitus
  4. Blood glucose increased
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Jaundice cholestatic
  8. Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen)
  9. Metastases to liver (cancer spreads to liver)
  10. Metastases to peritoneum (cancer spreads to peritoneum)

60+:

  1. Abscess (pus)
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Back pain
  4. Bone disorder
  5. Cardiac failure congestive
  6. Cardiomegaly (increased size of heart than normal)
  7. Cellulitis (infection under the skin)
  8. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Compression fracture (fracture due to pressure caused by injury)

What are the existing conditions these people have? *

  1. Depression: 2 people, 16.67%
  2. Bipolar Disorder (mood disorder): 2 people, 16.67%
  3. Type 2 Diabetes: 1 person, 8.33%
  4. Suicide Attempt: 1 person, 8.33%
  5. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  6. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 8.33%
  7. Insomnia (sleeplessness): 1 person, 8.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  9. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Haldol and Relafen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Haldol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Relafen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haldol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Relafen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on haloperidol and nabumetone (the active ingredients of Haldol and Relafen, respectively), and Haldol and Relafen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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