Halothane and Atropine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Halothane (halothane) and Atropine (atropine). Common drug interactions include anaphylactic reaction among females and cardiac arrest among males.
The phase IV clinical study analyzes what interactions people have when they take Halothane and Atropine. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.
What is Halothane?
Halothane has active ingredients of halothane. eHealthMe is studying from 312 Halothane users. Check the latest studies of Halothane.
What is Atropine?
Atropine has active ingredients of atropine. eHealthMe is studying from 8,693 Atropine users. Check the latest studies of Atropine.
68 people who take Halothane and Atropine together, and have interactions are studied.

What are the common drug interactions of Halothane and Atropine, by gender? *:
female:
- Anaphylactic reaction (serious allergic reaction)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Apnoea (suspension of external breathing)
- Ascites (accumulation of fluid in the abdominal cavity)
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
- Blood bilirubin increased
- Blood corticotrophin increased
- Blood cortisol decreased
- Blood creatine phosphokinase increased
- Blood thyroid stimulating hormone increased
male:
- Cardiac arrest
- Bradycardia (abnormally slow heart action)
- Myoglobinuria (presence of myoglobin in the urine)
- Pulmonary oedema (fluid accumulation in the lungs)
- Pyrexia (fever)
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
- Alanine aminotransferase increased
- Anaesthetic complication
- Arrhythmia (irregular heartbeat)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the common drug interactions of Halothane and Atropine, by age (0-1 to 60+)? *:
0-1:
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Apnoea (suspension of external breathing)
- Cyanosis neonatal (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails in newborn)
- Epiglottic oedema (swelling and inflammation of the epiglottis)
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Aortic valve disease
- Apgar score low
- Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
- Atrioventricular block (heart block)
- Blood amylase increased
2-9:
- Heart rate increased
- Hyperkalaemia (damage to or disease of the kidney)
- Hyperpyrexia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Joint stiffness
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Muscle spasms (muscle contraction)
- Mydriasis (a dilation of the pupil)
- Myoglobin urine present
- Neutrophilia
10-19:
- Pulmonary oedema (fluid accumulation in the lungs)
- Bradycardia (abnormally slow heart action)
- Drug exposure during pregnancy
- Drug toxicity
- Hypertension (high blood pressure)
- Premature labour
- Umbilical cord prolapse
- Anaesthetic complication
- Apnoea (suspension of external breathing)
- Blood pressure decreased
20-29:
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Cardiac arrest
- Coma (state of unconsciousness lasting more than six hours)
- Hypersensitivity
- Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
- Rash erythematous (redness of the skin)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Ventricular extrasystoles (premature cardiac contraction)
30-39:
- Hyperpyrexia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Blood ph decreased
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Cyanosis peripheral (blue tint in fingers or extremities, due to inadequate circulation)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Rhythm idioventricular (a abnormal heart rate)
40-49:
- Hypotension (abnormally low blood pressure)
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
- Blood corticotrophin increased
- Blood cortisol decreased
- Blood thyroid stimulating hormone increased
- Coma (state of unconsciousness lasting more than six hours)
- Endocrine disorder (endocrine diseases are disorders of the endocrine system)
- Heart rate decreased
- Hypertension (high blood pressure)
50-59:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Hepatitis (inflammation of the liver)
60+:
- Conjunctivitis (pink eye)
- Blood urea increased
- Mucosal erosion (peeling off of mucous membrane)
- Pneumonia
- Rash
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Apnoea (suspension of external breathing)
- Blood pressure decreased
What are the existing conditions these people have? *
- Anaesthesia: 13 people, 19.12%
* Approximation only. Some reports may have incomplete information.
Do you take Halothane and Atropine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Halothane and Atropine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Halothane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Atropine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Halothane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Atropine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on halothane and atropine (the active ingredients of Halothane and Atropine, respectively), and Halothane and Atropine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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