Dulcolax and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dulcolax (bisacodyl) and Prograf (tacrolimus). Common drug interactions include back pain among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Dulcolax and Prograf. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 19, 2026

43 people who take Dulcolax and Prograf together, and have interactions are studied.

What are the common drug interactions of Dulcolax and Prograf, by gender? *:

female:

Back pain
Bile duct stenosis (abnormal narrowing of the common bile duct)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fall
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)
Haematemesis (vomiting of blood)
Hypertension (high blood pressure)
Hysterectomy
Immunosuppressant drug level increased

male:

Blood creatinine increased
Fatigue (feeling of tiredness)
Chronic kidney disease
Renal failure (kidney dysfunction)
Arrhythmia (irregular heartbeat)
Head discomfort
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Anaemia (lack of blood)
Decreased appetite

What are the common drug interactions of Dulcolax and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Decreased appetite
Drug ineffective
Overdose
Gastroenteritis (inflammation of stomach and intestine)

30-39:

Arrhythmia (irregular heartbeat)
Cellulitis (infection under the skin)
Chest discomfort
Chest pain

40-49:

Abscess (pus)
Blood creatinine increased
Exostosis (formation of new bone on the surface of a bone)
International normalised ratio increased
Localised infection (infection at the single location)
Muscular weakness (muscle weakness)
Post procedural haemorrhage (post procedural bleeding)
Skin ulcer
Renal failure (kidney dysfunction)
Abdominal pain

50-59:

Head discomfort
Hypertension (high blood pressure)
Hysterectomy
Immunosuppressant drug level increased
Liver transplant rejection (failure of liver transplant)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Productive cough

60+:

Diarrhoea
Chronic kidney disease
Chest pain
Gait disturbance
Mobility decreased (ability to move is reduced)
Urinary tract infection
Anaemia (lack of blood)
Cardiac arrest
Failure to thrive (inadequate weight gain and physical growth in children)
Head discomfort

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 20.93%
Pain: 7 people, 16.28%
Nausea (feeling of having an urge to vomit): 5 people, 11.63%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 5 people, 11.63%
Insomnia (sleeplessness): 4 people, 9.30%
Immunodeficiency Disorders: 4 people, 9.30%
High Blood Cholesterol: 4 people, 9.30%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.30%
Diabetes: 4 people, 9.30%
Joint Pain: 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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