Naproxen and Diprolene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Diprolene (betamethasone dipropionate). Common drug interactions include paraesthesia among females and immunoglobulins decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Diprolene. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Diprolene?

Diprolene has active ingredients of betamethasone dipropionate. eHealthMe is studying from 1,048 Diprolene users. Check the latest studies of Diprolene.

On Jul, 19, 2026

23 people who take Naproxen and Diprolene together, and have interactions are studied.

Naproxen and Diprolene drug interactions.

What are the common drug interactions of Naproxen and Diprolene, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Sinusitis (inflammation of sinus)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Synovial cyst (cyst of joint filled with synovial fluid)
Urinary tract infection
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)

male:

Immunoglobulins decreased
Acute hepatic failure
Leukopenia (less number of white blood cells in blood)
Nasopharyngitis (inflammation of the nasopharynx)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Productive cough
Prostatomegaly (enlargement of the prostate)
Splenomegaly (enlargement of spleen)
Weight decreased
Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Naproxen and Diprolene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Skin discomfort (skin pain/irritation)

20-29:

n/a

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Actinic keratosis (skin disease due to sun exposure)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Anaemia macrocytic (a macrocytic class of anaemia)
Anaemia of malignant disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)

50-59:

Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Leukocytosis (increased white blood cells)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Pleural effusion (water on the lungs)
Proteinuria (presence of protein in the urine)
Renal failure chronic (long lasting kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Actinic keratosis (skin disease due to sun exposure)
Lipoma (a growth of fatty tissue that slowly develops just under your skin)

60+:

Bunion (a painful swelling on the first joint of the big toe)
Fall
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Spinal compression fracture (fracture due to spinal compression on bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Synovial cyst (cyst of joint filled with synovial fluid)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Abdominal discomfort
Acute hepatic failure
Aphthous ulcer (mouth ulcer)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 13 people, 56.52%
Bone Density Decreased: 6 people, 26.09%
Bone Loss: 5 people, 21.74%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 13.04%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.70%
Nosebleed (bleeding from nose): 2 people, 8.70%
High Blood Cholesterol: 2 people, 8.70%
Headache (pain in head): 2 people, 8.70%
Aphthous Stomatitis (mouth ulcer): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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