Creon and Affective disorder - a phase IV clinical study of FDA data

Summary:

Affective disorder is reported as a side effect among people who take Creon (pancrelipase (amylase;lipase;protease)), especially for people who are female, 10-19 old, have been taking the drug for 1 - 2 years also take Pulmozyme, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Affective disorder when taking Creon. It is created by eHealthMe based on reports of 29,220 people who have side effects when taking Creon from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Affective disorder?

Affective disorder (mental disorder) is found to be associated with 710 drugs and 783 conditions by eHealthMe. Check the latest studies of Affective disorder.

On Jul, 19, 2026

29,220 people reported to have side effects when taking Creon.
Among them, 17 people (0.06%) have Affective disorder.

Among these 17 people:

How long have people been on Creon when they have Affective disorder? *

What is the gender of people who have Affective disorder when taking Creon? *

female: 60 %
male: 40 %

What is the age of people who have Affective disorder when taking Creon? *

What are other drugs people take besides Creon? *

What are other side effects people have besides Affective disorder? *

Stress And Anxiety: 6 people, 35.29%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 5 people, 29.41%
Anger: 4 people, 23.53%
Suicidal Ideation: 4 people, 23.53%
Headache (pain in head): 4 people, 23.53%
Affect Lability (emotional incontinence): 3 people, 17.65%
Aggression: 3 people, 17.65%
Impulsive Behavior: 3 people, 17.65%
Hepatic Steatosis (fatty liver disease): 3 people, 17.65%
Depressive Symptom: 3 people, 17.65%

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 10 people, 58.82%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 11.76%
Body Temperature Increased: 2 people, 11.76%
Pneumonia: 2 people, 11.76%
Pain: 2 people, 11.76%
Constipation: 2 people, 11.76%
Gout (uric acid crystals building up in the body): 1 person, 5.88%
Cardiac Amyloidosis (protein deposition in heart): 1 person, 5.88%
Depressed Mood: 1 person, 5.88%
Itching: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and have Affective disorder?

- Check whether Affective disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Creon:

Creon (29,489 reports)

Affective disorder treatments and more:

Affective disorder (25,677 reports)

How severe was Affective disorder and when was it recovered:

Affective disorder in Creon

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Affective disorder and drugs with ingredients of pancrelipase (amylase;lipase;protease) (24 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Affective disorder:

Affective disorder (710 drugs)

Browse all the conditions that are associated with Affective disorder:

Affective disorder (783 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.